Abstract
Objectives: This study aimed to evaluate neonatal outcomes associated with birthweight discordance in twin pregnancies managed at a regional tertiary care centre in Oman. Methods: This five-year retrospective cohort study (2020–2024) was conducted at Nizwa Hospital, Nizwa, Oman, and included twin pregnancies of ≥ 24 weeks' gestation. Birthweight discordance was defined as ≥ 20%. Multivariable logistic regression analysis was performed, adjusting for gestational age at delivery, chorionicity, preeclampsia and gestational diabetes mellitus. Results: A total of 226 twin pregnancies were included, of which 45 (19.9%) had birthweight discordance ≥ 20%. Discordant pregnancies were delivered at an earlier gestational age than non-discordant pregnancies (34.2 ± 2.9 versus 35.3 ± 2.2 weeks; P = 0.017). NICU admission was more frequent in the discordant group (60.0% versus 31.5%; P <0.001), as was the composite adverse neonatal outcome (62.2% versus 33.1%; P <0.001). Birthweight discordance ≥ 20% remained independently associated with the composite adverse neonatal outcome (adjusted odds ratio [aOR] = 2.74, 95% CI: 1.21–6.25; P = 0.016), while increasing gestational age at delivery was protective (aOR = 0.47 per additional week, 95% CI: 0.37–0.59; P <0.001). Conclusion: Birthweight discordance ≥ 20% was associated with adverse neonatal outcomes in twin pregnancies, with this association largely mediated by prematurity.
Publication details
- DOI
- 10.18295/2075-0528.3011
- Journal
- Sultan Qaboos University Medical Journal, 26(1), 515-521
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY-ND 4.0
Cite this article
APA 7
Mahboubi, M., Al Saeghi, S. M. S., Dhar, H., El Fatah, D. M. A., Mensour, R. E. O., & Ambu-Saeidi, Q. K. S. (2026). Neonatal Outcomes in Twin Pregnancies with Birthweight Discordance: A five-year retrospective cohort study. Sultan Qaboos University Medical Journal, 26(1), 515-521. https://doi.org/10.18295/2075-0528.3011
MLA 9
Mahboubi, Marjan, et al. "Neonatal Outcomes in Twin Pregnancies with Birthweight Discordance: A five-year retrospective cohort study." Sultan Qaboos University Medical Journal, vol. 26, no. 1, 2026, pp. 515-521. https://doi.org/10.18295/2075-0528.3011.
Chicago (author–date)
Mahboubi, Marjan, Shadya Mohammed Salim Al Saeghi, Hansa Dhar, Dina Mohamed Abd El Fatah, Rowaida Elraih Omran Mensour, and Qamariya Khalfan Saud Ambu-Saeidi. 2026. "Neonatal Outcomes in Twin Pregnancies with Birthweight Discordance: A five-year retrospective cohort study." Sultan Qaboos University Medical Journal 26 (1): 515-521. https://doi.org/10.18295/2075-0528.3011.
Harvard
Mahboubi, M., Al Saeghi, S. M. S., Dhar, H., El Fatah, D. M. A., Mensour, R. E. O. and Ambu-Saeidi, Q. K. S. (2026) 'Neonatal Outcomes in Twin Pregnancies with Birthweight Discordance: A five-year retrospective cohort study', Sultan Qaboos University Medical Journal, 26(1), pp. 515-521. doi:10.18295/2075-0528.3011.
Vancouver
Mahboubi M, Al Saeghi SMS, Dhar H, El Fatah DMA, Mensour REO, Ambu-Saeidi QKS. Neonatal Outcomes in Twin Pregnancies with Birthweight Discordance: A five-year retrospective cohort study. Sultan Qaboos University Medical Journal. 2026;26(1):515-521. doi:10.18295/2075-0528.3011
IEEE
M. Mahboubi, S. M. S. Al Saeghi, H. Dhar, D. M. A. El Fatah, R. E. O. Mensour, and Q. K. S. Ambu-Saeidi, "Neonatal Outcomes in Twin Pregnancies with Birthweight Discordance: A five-year retrospective cohort study," Sultan Qaboos University Medical Journal, vol. 26, no. 1, pp. 515-521, 2026, doi: 10.18295/2075-0528.3011.