Abstract
Plasma cell myeloma is an uncommon disease which, besides primarily involving the bone marrow, has a tendency to involve other organs thus presenting with different clinical manifestations. While pleural effusions are infrequent in this disease, true myelomatous pleural effusions are extremely rare. We report the case of a middle-aged Omani man with relapsed plasma cell myeloma who developed bilateral pleural effusions. The diagnosis of myelomatous pleural effusion was made by finding many abnormal plasma cells as well as a high level of a monoclonal protein (IgG κ) in the pleural fluid. In spite of a good initial response to therapy, the patient had progressive disease and died 6 months later with bacterial sepsis. We present a review of the literature that indicates the rarity of such a manifestation and its association with poor prognosis and short survival.
Publication details
- DOI
- 10.18295/2075-0528.1272
- Journal
- Sultan Qaboos University Medical Journal, 11(2), 259-264
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY-ND 4.0
Cite this article
APA 7
Al-Farsi, K., Al Haddabi, I., Al-Sukaiti, N., Rashid, & Al Kindi, S. (2025). Myelomatous Pleural Effusion: Case report and review of the literature. Sultan Qaboos University Medical Journal, 11(2), 259-264. https://doi.org/10.18295/2075-0528.1272
MLA 9
Al-Farsi, Khalil, et al. "Myelomatous Pleural Effusion: Case report and review of the literature." Sultan Qaboos University Medical Journal, vol. 11, no. 2, 2025, pp. 259-264. https://doi.org/10.18295/2075-0528.1272.
Chicago (author–date)
Al-Farsi, Khalil, Ibrahim Al Haddabi, Nafla Al-Sukaiti, Rashid, and Salam Al Kindi. 2025. "Myelomatous Pleural Effusion: Case report and review of the literature." Sultan Qaboos University Medical Journal 11 (2): 259-264. https://doi.org/10.18295/2075-0528.1272.
Harvard
Al-Farsi, K., Al Haddabi, I., Al-Sukaiti, N., Rashid and Al Kindi, S. (2025) 'Myelomatous Pleural Effusion: Case report and review of the literature', Sultan Qaboos University Medical Journal, 11(2), pp. 259-264. doi:10.18295/2075-0528.1272.
Vancouver
Al-Farsi K, Al Haddabi I, Al-Sukaiti N, Rashid, Al Kindi S. Myelomatous Pleural Effusion: Case report and review of the literature. Sultan Qaboos University Medical Journal. 2025;11(2):259-264. doi:10.18295/2075-0528.1272
IEEE
K. Al-Farsi, I. Al Haddabi, N. Al-Sukaiti, Rashid, and S. Al Kindi, "Myelomatous Pleural Effusion: Case report and review of the literature," Sultan Qaboos University Medical Journal, vol. 11, no. 2, pp. 259-264, 2025, doi: 10.18295/2075-0528.1272.