Abstract
Background: To evaluate retinal structural and vascular changes using optical coherence 15 tomography (OCT) and OCT angiography (OCT-A) in migraine patients and to explore 16 their associations with clinical and epidemiological characteristics. Subjects and methods: This cross-sectional, comparative study included 136 eyes from 68 subjects, divided into 68 eyes from migraine patients and 68 eyes from controls. Participants underwent full ophthalmological examinations, OCT, and OCT-A. Results: Patients had a mean age of 35.8 years and a female-to-male ratio of 1.83. Migraine with aura was present in 47.1% of cases. A reduction in upper retinal nerve fiber layer thickness was found in migraine patients, with no other significant OCT or OCT-A differences compared to controls. Correlations were observed between OCT metrics and disease duration, severity, and attack frequency, though no correlations were noted with laterality. Conclusion: Optical coherence tomography and optical coherence tomography-angiography may serve as valuable biomarkers for diagnosing, monitoring, and predicting outcomes in both aura and nonaura migraines.
Keywords
Subject
Publication details
- DOI
- 10.4103/ojo.ojo_428_25
- Journal
- Oman Journal of Ophthalmology, 19(2), 210-216
- Publisher
- Medknow Publications
- Open access
- Gold open access
Cite this article
APA 7
Khallouli, A., Jabri, A., Ben Abderazek, A., Oueslati, Y., & Maalej, A. (2026). Multimodal retinal imaging in migraine: Structural and vascular correlates of clinical characteristics. Oman Journal of Ophthalmology, 19(2), 210-216. https://doi.org/10.4103/ojo.ojo_428_25
MLA 9
Khallouli, Asma, et al. "Multimodal retinal imaging in migraine: Structural and vascular correlates of clinical characteristics." Oman Journal of Ophthalmology, vol. 19, no. 2, 2026, pp. 210-216. https://doi.org/10.4103/ojo.ojo_428_25.
Chicago (author–date)
Khallouli, Asma, Ahmed Jabri, Atf Ben Abderazek, Yassin Oueslati, and Afef Maalej. 2026. "Multimodal retinal imaging in migraine: Structural and vascular correlates of clinical characteristics." Oman Journal of Ophthalmology 19 (2): 210-216. https://doi.org/10.4103/ojo.ojo_428_25.
Harvard
Khallouli, A., Jabri, A., Ben Abderazek, A., Oueslati, Y. and Maalej, A. (2026) 'Multimodal retinal imaging in migraine: Structural and vascular correlates of clinical characteristics', Oman Journal of Ophthalmology, 19(2), pp. 210-216. doi:10.4103/ojo.ojo_428_25.
Vancouver
Khallouli A, Jabri A, Ben Abderazek A, Oueslati Y, Maalej A. Multimodal retinal imaging in migraine: Structural and vascular correlates of clinical characteristics. Oman Journal of Ophthalmology. 2026;19(2):210-216. doi:10.4103/ojo.ojo_428_25
IEEE
A. Khallouli, A. Jabri, A. Ben Abderazek, Y. Oueslati, and A. Maalej, "Multimodal retinal imaging in migraine: Structural and vascular correlates of clinical characteristics," Oman Journal of Ophthalmology, vol. 19, no. 2, pp. 210-216, 2026, doi: 10.4103/ojo.ojo_428_25.