Abstract
Two infants with retinoblastoma and 13q syndrome with multiorgan system anomalies were treated with targeted intra-arterial chemotherapy (IAC) using one-to-three cycles of melphalan 5 mg to avoid systemic chemotherapeutic side effects. Both patients showed good response, with tumor control and no systemic chemotherapy side effects. Of the treatment modalities currently available, IAC may represent an optimal balance between tumor extermination and adverse drug reactions in this patient population with classically reduced multiorgan reserve.
Keywords
Publication details
- DOI
- 10.4103/0974-620x.192278
- Journal
- Oman Journal of Ophthalmology, 9(3), 164-166
- Publisher
- Medknow Publications
- Open access
- Gold open access
Cite this article
APA 7
Dillon, A. B., Douglass, A., Jabbour, P., & Shields, C. L. (2016). Minimal exposure intra-arterial chemotherapy for children with retinoblastoma and 13q syndrome. Oman Journal of Ophthalmology, 9(3), 164-166. https://doi.org/10.4103/0974-620x.192278
MLA 9
Dillon, Alexander B, et al. "Minimal exposure intra-arterial chemotherapy for children with retinoblastoma and 13q syndrome." Oman Journal of Ophthalmology, vol. 9, no. 3, 2016, pp. 164-166. https://doi.org/10.4103/0974-620x.192278.
Chicago (author–date)
Dillon, Alexander B, Alexzandra Douglass, Pascal Jabbour, and Carol L Shields. 2016. "Minimal exposure intra-arterial chemotherapy for children with retinoblastoma and 13q syndrome." Oman Journal of Ophthalmology 9 (3): 164-166. https://doi.org/10.4103/0974-620x.192278.
Harvard
Dillon, A. B., Douglass, A., Jabbour, P. and Shields, C. L. (2016) 'Minimal exposure intra-arterial chemotherapy for children with retinoblastoma and 13q syndrome', Oman Journal of Ophthalmology, 9(3), pp. 164-166. doi:10.4103/0974-620x.192278.
Vancouver
Dillon AB, Douglass A, Jabbour P, Shields CL. Minimal exposure intra-arterial chemotherapy for children with retinoblastoma and 13q syndrome. Oman Journal of Ophthalmology. 2016;9(3):164-166. doi:10.4103/0974-620x.192278
IEEE
A. B. Dillon, A. Douglass, P. Jabbour, and C. L. Shields, "Minimal exposure intra-arterial chemotherapy for children with retinoblastoma and 13q syndrome," Oman Journal of Ophthalmology, vol. 9, no. 3, pp. 164-166, 2016, doi: 10.4103/0974-620x.192278.