Abstract
Metformin is a widely used biguanide for the treatment of type 2 diabetes mellitus. Metformin-induced lactic acidosis (MALA) is a rare but potentially fatal entity in the pediatric age group, seen mainly in suicide attempts in adolescents. MALA has not yet been reported in younger patients or pediatric patients taking regular therapeutic doses. Here, we report a three-year-old female receiving therapeutic metformin who developed MALA. MALA should be suspected in patients with unexplained lactic acidosis and on regular metformin, especially in the setting of renal impairment or hypoxic events.
Keywords
Publication details
- DOI
- 10.5001/omj.2020.104
- Journal
- Oman Medical Journal
- Publisher
- Oman Medical Specialty Board
- Open access
- Gold open access
Cite this article
APA 7
Al-Abdwani, R. (2020). Metformin-induced Lactic Acidosis Reported in the Youngest Pediatric Patient with Impaired Renal Function. Oman Medical Journal. https://doi.org/10.5001/omj.2020.104
MLA 9
Al-Abdwani, Raghad. "Metformin-induced Lactic Acidosis Reported in the Youngest Pediatric Patient with Impaired Renal Function." Oman Medical Journal, 2020. https://doi.org/10.5001/omj.2020.104.
Chicago (author–date)
Al-Abdwani, Raghad. 2020. "Metformin-induced Lactic Acidosis Reported in the Youngest Pediatric Patient with Impaired Renal Function." Oman Medical Journal. https://doi.org/10.5001/omj.2020.104.
Harvard
Al-Abdwani, R. (2020) 'Metformin-induced Lactic Acidosis Reported in the Youngest Pediatric Patient with Impaired Renal Function', Oman Medical Journal. doi:10.5001/omj.2020.104.
Vancouver
Al-Abdwani R. Metformin-induced Lactic Acidosis Reported in the Youngest Pediatric Patient with Impaired Renal Function. Oman Medical Journal. 2020. doi:10.5001/omj.2020.104
IEEE
R. Al-Abdwani, "Metformin-induced Lactic Acidosis Reported in the Youngest Pediatric Patient with Impaired Renal Function," Oman Medical Journal, 2020, doi: 10.5001/omj.2020.104.