Abstract

Kikuchi disease is a rare condition, typically characterized by cervical lymphadenopathy and fever. Although its association with systemic lupus erythematosus (SLE) is well established, the majority of SLE cases do not present with Kikuchi disease. We report a case of a young patient who presented with fever and cervical lymphadenopathies for two-weeks. This presents a broad differential, initially suggesting the possibility of infections or malignancies. However, after further clinical evaluation, including cervical node biopsy, direct histological examination revealed Kikuchi disease. Combining all clinical information and laboratory data, we concluded that the patient’s condition was consistent with Kikuchi disease associated with SLE and probable autoimmune hepatitis. This case illustrates a young female patient with clinical presentations of SLE associated with Kikuchi disease as the first manifestation.

Keywords

Publication details

DOI
10.5001/omj.2025.23
Journal
Oman Medical Journal, 40(4)
Publisher
Oman Medical Specialty Board
Open access
Gold open access
License
CC BY-NC 4.0

Cite this article

APA 7

YW, C., Malehah, M. N., Hairul, H., & Shahleni, P. (2025). Kikuchi Disease Unveiling Systemic Lupus Erythematosus: A Rare Case of Initial Manifestation. Oman Medical Journal, 40(4). https://doi.org/10.5001/omj.2025.23

MLA 9

YW, Cheong, et al. "Kikuchi Disease Unveiling Systemic Lupus Erythematosus: A Rare Case of Initial Manifestation." Oman Medical Journal, vol. 40, no. 4, 2025. https://doi.org/10.5001/omj.2025.23.

Chicago (author–date)

YW, Cheong, Mohd Noh Malehah, Hadi Hairul, and Paramasivam Shahleni. 2025. "Kikuchi Disease Unveiling Systemic Lupus Erythematosus: A Rare Case of Initial Manifestation." Oman Medical Journal 40 (4). https://doi.org/10.5001/omj.2025.23.

Harvard

YW, C., Malehah, M. N., Hairul, H. and Shahleni, P. (2025) 'Kikuchi Disease Unveiling Systemic Lupus Erythematosus: A Rare Case of Initial Manifestation', Oman Medical Journal, 40(4). doi:10.5001/omj.2025.23.

Vancouver

YW C, Malehah MN, Hairul H, Shahleni P. Kikuchi Disease Unveiling Systemic Lupus Erythematosus: A Rare Case of Initial Manifestation. Oman Medical Journal. 2025;40(4). doi:10.5001/omj.2025.23

IEEE

C. YW, M. N. Malehah, H. Hairul, and P. Shahleni, "Kikuchi Disease Unveiling Systemic Lupus Erythematosus: A Rare Case of Initial Manifestation," Oman Medical Journal, vol. 40, no. 4, 2025, doi: 10.5001/omj.2025.23.