Abstract
We report the effects of intravitreal ranibizumab as salvage therapy in an extremely low-birth-weight (ELBW) infant with rush type retinopathy of prematurity (ROP). This case was a girl of 23 weeks gestational age weighing 480 g at birth. At a postconceptual age of 33 weeks, she presented with zone 1, stage 3 ROP with plus disease. Despite intravitreal bevazucimab and laser photocoagulation, extraretinal fibrovascular proliferation persisted. Intravitreal 0.25 mg (0.025 ml) ranibizumab was injected OU. After treatment, extraretinal fibrovascular proliferation disappeared. Fundus examination showed flat retinas and normal vasculature in both eyes. She has been followed up for 2 years. Intravitreal ranibizumab injection seems effective and well tolerated as salvage therapy in an ELBW infant with rush type ROP. No short-term ocular or systemic side effects were identified. More cases and longer follow-up are mandatory.
Keywords
Publication details
- DOI
- 10.4103/0974-620x.106103
- Journal
- Oman Journal of Ophthalmology, 5(3), 184-186
- Publisher
- Medknow Publications
- Open access
- Gold open access
Cite this article
APA 7
Lin, C. J., Chen, S. N., & Hwang, J. F. (2012). Intravitreal ranibizumab as salvage therapy in an extremely low-birth-weight infant with rush type retinopathy of prematurity. Oman Journal of Ophthalmology, 5(3), 184-186. https://doi.org/10.4103/0974-620x.106103
MLA 9
Lin, Chun-Ju, et al. "Intravitreal ranibizumab as salvage therapy in an extremely low-birth-weight infant with rush type retinopathy of prematurity." Oman Journal of Ophthalmology, vol. 5, no. 3, 2012, pp. 184-186. https://doi.org/10.4103/0974-620x.106103.
Chicago (author–date)
Lin, Chun-Ju, San-Ni Chen, and Jiunn-Feng Hwang. 2012. "Intravitreal ranibizumab as salvage therapy in an extremely low-birth-weight infant with rush type retinopathy of prematurity." Oman Journal of Ophthalmology 5 (3): 184-186. https://doi.org/10.4103/0974-620x.106103.
Harvard
Lin, C. J., Chen, S. N. and Hwang, J. F. (2012) 'Intravitreal ranibizumab as salvage therapy in an extremely low-birth-weight infant with rush type retinopathy of prematurity', Oman Journal of Ophthalmology, 5(3), pp. 184-186. doi:10.4103/0974-620x.106103.
Vancouver
Lin CJ, Chen SN, Hwang JF. Intravitreal ranibizumab as salvage therapy in an extremely low-birth-weight infant with rush type retinopathy of prematurity. Oman Journal of Ophthalmology. 2012;5(3):184-186. doi:10.4103/0974-620x.106103
IEEE
C. J. Lin, S. N. Chen, and J. F. Hwang, "Intravitreal ranibizumab as salvage therapy in an extremely low-birth-weight infant with rush type retinopathy of prematurity," Oman Journal of Ophthalmology, vol. 5, no. 3, pp. 184-186, 2012, doi: 10.4103/0974-620x.106103.