Abstract

Acute optic neuritis (ON) is caused by variety of complex disorders that can be differentiated with the help of history, radiology, and serology. Identification of nonneurological symptoms that occur before the demyelinating event aids in timely diagnosis and prevention of further neurological attacks. We describe a case of unilateral ON with a history of intractable hiccups, nausea, and vomiting, wherein the possibility of area postrema syndrome (APS) was overlooked until the development of visual symptoms. APS recently identified as a hallmark of neuromyelitis optica spectrum disorder is a rare neurologic cause of gastrointestinal symptoms. This atypical presentation of APS results from autoantibodies directed against the aquaporin-4 rich sites, such as area postrema. This case brings to light the importance of eliciting history of intractable hiccups, nausea, and vomiting in a patient with ON. Despite being a commonly encountered symptom, it may rarely raise a suspicion for neuromyelitis optica.

Keywords

Publication details

DOI
10.4103/ojo.ojo_65_21
Journal
Oman Journal of Ophthalmology, 15(3), 366-369
Publisher
Medknow Publications
Open access
Gold open access

Cite this article

APA 7

Kumar, S. M., Venkatraman, V., Kowsalya, A., Narayanamoorthy, J., & Jayasudha, M. (2022). Intractable hiccups, nausea, and vomiting, an unnerving cause of vision loss. Oman Journal of Ophthalmology, 15(3), 366-369. https://doi.org/10.4103/ojo.ojo_65_21

MLA 9

Kumar, Shanmugam Mahesh, et al. "Intractable hiccups, nausea, and vomiting, an unnerving cause of vision loss." Oman Journal of Ophthalmology, vol. 15, no. 3, 2022, pp. 366-369. https://doi.org/10.4103/ojo.ojo_65_21.

Chicago (author–date)

Kumar, Shanmugam Mahesh, Vaishali Venkatraman, Akkayasamy Kowsalya, Jayasri Narayanamoorthy, and Marappan Jayasudha. 2022. "Intractable hiccups, nausea, and vomiting, an unnerving cause of vision loss." Oman Journal of Ophthalmology 15 (3): 366-369. https://doi.org/10.4103/ojo.ojo_65_21.

Harvard

Kumar, S. M., Venkatraman, V., Kowsalya, A., Narayanamoorthy, J. and Jayasudha, M. (2022) 'Intractable hiccups, nausea, and vomiting, an unnerving cause of vision loss', Oman Journal of Ophthalmology, 15(3), pp. 366-369. doi:10.4103/ojo.ojo_65_21.

Vancouver

Kumar SM, Venkatraman V, Kowsalya A, Narayanamoorthy J, Jayasudha M. Intractable hiccups, nausea, and vomiting, an unnerving cause of vision loss. Oman Journal of Ophthalmology. 2022;15(3):366-369. doi:10.4103/ojo.ojo_65_21

IEEE

S. M. Kumar, V. Venkatraman, A. Kowsalya, J. Narayanamoorthy, and M. Jayasudha, "Intractable hiccups, nausea, and vomiting, an unnerving cause of vision loss," Oman Journal of Ophthalmology, vol. 15, no. 3, pp. 366-369, 2022, doi: 10.4103/ojo.ojo_65_21.