Abstract
The coexistence of cystic fibrosis (CF) and sarcoidosis is rare. We report a 22-year-old male cystic fibrosis patient who presented multiple times to the Sultan Qaboos University Hospital, Muscat, Oman, in 2013. He was diagnosed with non-parathyroid-related hypercalcaemia and anterior uveitis, while computed tomography revealed mediastinal and abdominal lymphadenopathy and mild hepatosplenomegaly. These findings, in addition to the presence of calciuria and a high angiotensin-converting enzyme (ACE) level, confirmed a clinical diagnosis of sarcoidosis. The patient responded well to treatment with oral prednisolone which, over the course of two years, resulted in the near-complete resolution of parenchymal nodular infiltrates, regression of hilar lymphadenopathy, resolution of hypercalcaemia and the normalisation of his ACE levels. Diagnosing pulmonary sarcoidosis in CF can be challenging as most adult patients already have extensive lung disease. Physicians should be aware that hypercalcaemia may be an early manifestation of sarcoidosis in such cases.
Publication details
- DOI
- 10.18295/squmj.2018.18.04.018
- Journal
- Sultan Qaboos University Medical Journal, 18(4), e533-536
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY-ND 4.0
Cite this article
APA 7
B, J., Al-Mubaihsi, S. M., George, M. S., & Jojy (2025). Hypercalcaemia: A portent of sarcoidosis in cystic fibrosis. Sultan Qaboos University Medical Journal, 18(4), e533-536. https://doi.org/10.18295/squmj.2018.18.04.018
MLA 9
B, Jayakrishnan, et al. "Hypercalcaemia: A portent of sarcoidosis in cystic fibrosis." Sultan Qaboos University Medical Journal, vol. 18, no. 4, 2025, pp. e533-536. https://doi.org/10.18295/squmj.2018.18.04.018.
Chicago (author–date)
B, Jayakrishnan, Saif M. Al-Mubaihsi, Masoud S. George, and Jojy. 2025. "Hypercalcaemia: A portent of sarcoidosis in cystic fibrosis." Sultan Qaboos University Medical Journal 18 (4): e533-536. https://doi.org/10.18295/squmj.2018.18.04.018.
Harvard
B, J., Al-Mubaihsi, S. M., George, M. S. and Jojy (2025) 'Hypercalcaemia: A portent of sarcoidosis in cystic fibrosis', Sultan Qaboos University Medical Journal, 18(4), pp. e533-536. doi:10.18295/squmj.2018.18.04.018.
Vancouver
B J, Al-Mubaihsi SM, George MS, Jojy. Hypercalcaemia: A portent of sarcoidosis in cystic fibrosis. Sultan Qaboos University Medical Journal. 2025;18(4):e533-536. doi:10.18295/squmj.2018.18.04.018
IEEE
J. B, S. M. Al-Mubaihsi, M. S. George, and Jojy, "Hypercalcaemia: A portent of sarcoidosis in cystic fibrosis," Sultan Qaboos University Medical Journal, vol. 18, no. 4, pp. e533-536, 2025, doi: 10.18295/squmj.2018.18.04.018.