Abstract
Objectives: The purpose of the present study was to determine the alterations in high-sensitivity C-reactive protein and Tumor Necrosis factor alpha levels in the blood serum of pseudoexfoliation syndrome cases (a disease with similar risk factors as systemic endothelial dysfunction diseases) and to compare the results with healthy individuals. Methods: High-sensitivity C-reactive protein and Tumor Necrosis factor alpha levels were determined in 30 cases with pseudoexfoliation syndrome and in 30 control patients of the same age and sex, by enzyme-linked immunosorbent assay. Results: The levels of high- sensitivity C-reactive protein and Tumor Necrosis factor alpha in the blood serum of patients with pseudoexfoliation syndrome (3.95±0.88 mg/l, 3.32±0.99 pg/ml, respectively) were significantly higher than in the control group (2.51±0.79mg/l, 0.43±0.15 pg/ml, respectively) p=0.001, p=0.002. Conclusion: The results suggest that increased levels of high- sensitivity C-reactive protein and Tumor Necrosis factor alpha, as markers of inflammation and peripheral endothelial dysfunction in pseudoexfoliation syndrome, may be risk factors for systemic and ocular manifestations of pseudoexfoliation syndrome.
Keywords
Publication details
- DOI
- 10.5001/omj.2013.04
- Journal
- Oman Medical Journal
- Publisher
- Oman Medical Specialty Board
- Open access
- Gold open access
Cite this article
APA 7
Sorkhabi, R., Ghorbanihaghjo, A., Ahoor, M., Nahaei, M., & Rashtchizadeh, N. (2013). High-sensitivity C-reactive Protein and Tumor Necrosis Factor Alpha in Pseudoexfoliation Syndrome. Oman Medical Journal. https://doi.org/10.5001/omj.2013.04
MLA 9
Sorkhabi, Rana, et al. "High-sensitivity C-reactive Protein and Tumor Necrosis Factor Alpha in Pseudoexfoliation Syndrome." Oman Medical Journal, 2013. https://doi.org/10.5001/omj.2013.04.
Chicago (author–date)
Sorkhabi, Rana, Amir Ghorbanihaghjo, Mohamadhossein Ahoor, Mehriar Nahaei, and Nadereh Rashtchizadeh. 2013. "High-sensitivity C-reactive Protein and Tumor Necrosis Factor Alpha in Pseudoexfoliation Syndrome." Oman Medical Journal. https://doi.org/10.5001/omj.2013.04.
Harvard
Sorkhabi, R., Ghorbanihaghjo, A., Ahoor, M., Nahaei, M. and Rashtchizadeh, N. (2013) 'High-sensitivity C-reactive Protein and Tumor Necrosis Factor Alpha in Pseudoexfoliation Syndrome', Oman Medical Journal. doi:10.5001/omj.2013.04.
Vancouver
Sorkhabi R, Ghorbanihaghjo A, Ahoor M, Nahaei M, Rashtchizadeh N. High-sensitivity C-reactive Protein and Tumor Necrosis Factor Alpha in Pseudoexfoliation Syndrome. Oman Medical Journal. 2013. doi:10.5001/omj.2013.04
IEEE
R. Sorkhabi, A. Ghorbanihaghjo, M. Ahoor, M. Nahaei, and N. Rashtchizadeh, "High-sensitivity C-reactive Protein and Tumor Necrosis Factor Alpha in Pseudoexfoliation Syndrome," Oman Medical Journal, 2013, doi: 10.5001/omj.2013.04.