Abstract
We report a case of recurrence of herpes simplex virus (HSV) keratouveitis following the intravitreal injection of bevacizumab for macular edema secondary to central retinal vein occlusion (CRVO) in a previously adequately treated patient of herpetic keratouveitis. A 47-year-old man with the previous history of HSV keratouveitis was administered 2 doses of intravitreal bevacizumab in the right eye for CRVO, at an interval of 4 weeks. Following the second dose, the patient developed decreased vision, corneal edema, and anterior segment inflammation. Since he was a previously known case of HSV keratouveitis with a positive polymerase chain reaction for HSV from the aqueous, oral valacyclovir was started along with topical steroids and cycloplegics. He showed a good response to treatment with resolution of keratouveitis. This case demonstrates that the recurrence of herpetic keratouveitis can be a possible complication of intravitreal bevacizumab, which may occur even after prior uneventful injections.
Keywords
Publication details
- DOI
- 10.4103/ojo.ojo_147_2016
- Journal
- Oman Journal of Ophthalmology, 12(1), 53-54
- Publisher
- Medknow Publications
- Open access
- Gold open access
Cite this article
APA 7
Sharma, A., Singh, S. R., Dogra, M., Singh, C., & Singh, R. (2019). Herpes simplex virus keratouveitis recurrence following intravitreal bevacizumab injection. Oman Journal of Ophthalmology, 12(1), 53-54. https://doi.org/10.4103/ojo.ojo_147_2016
MLA 9
Sharma, Ashok, et al. "Herpes simplex virus keratouveitis recurrence following intravitreal bevacizumab injection." Oman Journal of Ophthalmology, vol. 12, no. 1, 2019, pp. 53-54. https://doi.org/10.4103/ojo.ojo_147_2016.
Chicago (author–date)
Sharma, Ashok, Simar Rajan Singh, Mohit Dogra, Chintan Singh, and Ramandeep Singh. 2019. "Herpes simplex virus keratouveitis recurrence following intravitreal bevacizumab injection." Oman Journal of Ophthalmology 12 (1): 53-54. https://doi.org/10.4103/ojo.ojo_147_2016.
Harvard
Sharma, A., Singh, S. R., Dogra, M., Singh, C. and Singh, R. (2019) 'Herpes simplex virus keratouveitis recurrence following intravitreal bevacizumab injection', Oman Journal of Ophthalmology, 12(1), pp. 53-54. doi:10.4103/ojo.ojo_147_2016.
Vancouver
Sharma A, Singh SR, Dogra M, Singh C, Singh R. Herpes simplex virus keratouveitis recurrence following intravitreal bevacizumab injection. Oman Journal of Ophthalmology. 2019;12(1):53-54. doi:10.4103/ojo.ojo_147_2016
IEEE
A. Sharma, S. R. Singh, M. Dogra, C. Singh, and R. Singh, "Herpes simplex virus keratouveitis recurrence following intravitreal bevacizumab injection," Oman Journal of Ophthalmology, vol. 12, no. 1, pp. 53-54, 2019, doi: 10.4103/ojo.ojo_147_2016.