Abstract
Pre-analytical quality in clinical chemistry testing is as important as analytical and post-analytical quality. The most prevalent pre-analytical interference and a major source of error producing unreliable laboratory test results is hemolysis of blood samples. In vitro hemolysis may be due to the blood withdrawal technique or sample handling whereas in vivo hemolysis can originate from acquired, hereditary, or iatrogenic conditions and is not technique dependent. Interpreting in vivo or in vitro hemolysis requires clinicians to supply reliable clinical history and findings. Even then, to reject or release the result with interpretation is still under debate. Thus, hemolyzed specimens are a serious pre-analytical problem calling for well-designed and strictly implemented laboratory guidelines. The aim of this non-systematic review (addressed to healthcare professionals) was to highlight the challenges in identifying and rejecting hemolysis specimens.
Keywords
Publication details
- DOI
- 10.5001/omj.2019.19
- Journal
- Oman Medical Journal
- Publisher
- Oman Medical Specialty Board
- Open access
- Gold open access
Cite this article
APA 7
Azman, W. N. W., Omar, J., Koon, T. S., & Ismail, T. S. T. (2019). Hemolyzed Specimens: Major Challenge for Identifying and Rejecting Specimens in Clinical Laboratories. Oman Medical Journal. https://doi.org/10.5001/omj.2019.19
MLA 9
Azman, Wan Norlina Wan, et al. "Hemolyzed Specimens: Major Challenge for Identifying and Rejecting Specimens in Clinical Laboratories." Oman Medical Journal, 2019. https://doi.org/10.5001/omj.2019.19.
Chicago (author–date)
Azman, Wan Norlina Wan, Julia Omar, Tan Say Koon, and Tuan Salwani Tuan Ismail. 2019. "Hemolyzed Specimens: Major Challenge for Identifying and Rejecting Specimens in Clinical Laboratories." Oman Medical Journal. https://doi.org/10.5001/omj.2019.19.
Harvard
Azman, W. N. W., Omar, J., Koon, T. S. and Ismail, T. S. T. (2019) 'Hemolyzed Specimens: Major Challenge for Identifying and Rejecting Specimens in Clinical Laboratories', Oman Medical Journal. doi:10.5001/omj.2019.19.
Vancouver
Azman WNW, Omar J, Koon TS, Ismail TST. Hemolyzed Specimens: Major Challenge for Identifying and Rejecting Specimens in Clinical Laboratories. Oman Medical Journal. 2019. doi:10.5001/omj.2019.19
IEEE
W. N. W. Azman, J. Omar, T. S. Koon, and T. S. T. Ismail, "Hemolyzed Specimens: Major Challenge for Identifying and Rejecting Specimens in Clinical Laboratories," Oman Medical Journal, 2019, doi: 10.5001/omj.2019.19.