Abstract
Aim: The aim of this study is to evaluate the efficacy of 2% rebamipide ophthalmic solution on the tear functions and ocular surface status in patients with dry eyes. Materials and methods: A prospective study was carried out on forty eyes of patients having signs and symptoms of dry eye. Two percent rebamipide ophthalmic solution was applied four times a day for a period of 4 weeks. Patients were evaluated on the basis of dry eye-related symptom score, tear film break-up time (TFBUT), tear meniscus height, fluorescein ocular surface staining score (FOSS), and the Schirmer's test at the end of 2, 4, 6, and 12 weeks and their values were compared with the baseline. Results: Significant improvement was noted in the mean dry eye-related symptom score, TBUT, and the FOSS values from the baseline at the end of 2, 4, 8, and 12 weeks. The values of tear meniscus height and Schirmer's test were improved at the end of 8 weeks but were not statistically significant. Conclusion: Nearly 2% rebamipide ophthalmic solution provided relief in the symptoms of patients having dry eyes. It also prevented further ocular surface damage and aided in stabilizing the tear film.
Keywords
Publication details
- DOI
- 10.4103/ojo.ojo_29_2017
- Journal
- Oman Journal of Ophthalmology, 11(3), 207-212
- Publisher
- Medknow Publications
- Open access
- Gold open access
Cite this article
APA 7
Shrivastava, S., Patkar, P., Ramakrishnan, R., Kanhere, M., & Riaz, Z. (2018). Efficacy of rebamipide 2% ophthalmic solution in the treatment of dry eyes. Oman Journal of Ophthalmology, 11(3), 207-212. https://doi.org/10.4103/ojo.ojo_29_2017
MLA 9
Shrivastava, Saurabh, et al. "Efficacy of rebamipide 2% ophthalmic solution in the treatment of dry eyes." Oman Journal of Ophthalmology, vol. 11, no. 3, 2018, pp. 207-212. https://doi.org/10.4103/ojo.ojo_29_2017.
Chicago (author–date)
Shrivastava, Saurabh, Priyanka Patkar, Reshma Ramakrishnan, Minal Kanhere, and Zahna Riaz. 2018. "Efficacy of rebamipide 2% ophthalmic solution in the treatment of dry eyes." Oman Journal of Ophthalmology 11 (3): 207-212. https://doi.org/10.4103/ojo.ojo_29_2017.
Harvard
Shrivastava, S., Patkar, P., Ramakrishnan, R., Kanhere, M. and Riaz, Z. (2018) 'Efficacy of rebamipide 2% ophthalmic solution in the treatment of dry eyes', Oman Journal of Ophthalmology, 11(3), pp. 207-212. doi:10.4103/ojo.ojo_29_2017.
Vancouver
Shrivastava S, Patkar P, Ramakrishnan R, Kanhere M, Riaz Z. Efficacy of rebamipide 2% ophthalmic solution in the treatment of dry eyes. Oman Journal of Ophthalmology. 2018;11(3):207-212. doi:10.4103/ojo.ojo_29_2017
IEEE
S. Shrivastava, P. Patkar, R. Ramakrishnan, M. Kanhere, and Z. Riaz, "Efficacy of rebamipide 2% ophthalmic solution in the treatment of dry eyes," Oman Journal of Ophthalmology, vol. 11, no. 3, pp. 207-212, 2018, doi: 10.4103/ojo.ojo_29_2017.