Abstract
This study evaluated the effects of magnesium (Mg) supplementation on glycaemic control in type 2 diabetes mellitus through a meta-analysis of 23 randomised controlled trials involving 1,345 participants. Mg supplementation significantly increased serum Mg levels (weighted mean difference [WMD] = 0.69, 95% CI: 0.32 to 1.06) and reduced fasting blood glucose levels (WMD = -0.58, 95% CI: -0.87 to -0.28). However, the impact on glycated haemoglobin was minimal (WMD = -0.16, 95% CI: -0.32 to 0.00). Subgroup analysis showed a greater reduction in glycated haemoglobin among participants aged ≥65 years and those receiving longer durations of supplementation. Additionally, Mg supplementation was linked to lower diastolic blood pressure and potential improvements in lipid profile. This review highlights the importance of considering patient characteristics, dosage and intervention duration in future research on Mg supplementation for glycaemic control in diabetes.
Publication details
- DOI
- 10.18295/2075-0528.2848
- Journal
- Sultan Qaboos University Medical Journal, 25(1), 382-394
- Publisher
- Sultan Qaboos University
- Open access
- Gold open access
- License
- CC BY-ND 4.0
Cite this article
APA 7
Al-Maqrashi, N., Al Busaidi, S., Al Rasbi, S., Al Alawi, A. M., & Al-Maqbali, J. S. (2025). Effect of Magnesium Supplements on Improving Glucose Control, Blood Pressure and Lipid Profile in Patients With Type 2 Diabetes Mellitus: A systematic review and meta-analysis. Sultan Qaboos University Medical Journal, 25(1), 382-394. https://doi.org/10.18295/2075-0528.2848
MLA 9
Al-Maqrashi, Nasiba, et al. "Effect of Magnesium Supplements on Improving Glucose Control, Blood Pressure and Lipid Profile in Patients With Type 2 Diabetes Mellitus: A systematic review and meta-analysis." Sultan Qaboos University Medical Journal, vol. 25, no. 1, 2025, pp. 382-394. https://doi.org/10.18295/2075-0528.2848.
Chicago (author–date)
Al-Maqrashi, Nasiba, Salim Al Busaidi, Sara Al Rasbi, Abdullah M. Al Alawi, and Juhaina S. Al-Maqbali. 2025. "Effect of Magnesium Supplements on Improving Glucose Control, Blood Pressure and Lipid Profile in Patients With Type 2 Diabetes Mellitus: A systematic review and meta-analysis." Sultan Qaboos University Medical Journal 25 (1): 382-394. https://doi.org/10.18295/2075-0528.2848.
Harvard
Al-Maqrashi, N., Al Busaidi, S., Al Rasbi, S., Al Alawi, A. M. and Al-Maqbali, J. S. (2025) 'Effect of Magnesium Supplements on Improving Glucose Control, Blood Pressure and Lipid Profile in Patients With Type 2 Diabetes Mellitus: A systematic review and meta-analysis', Sultan Qaboos University Medical Journal, 25(1), pp. 382-394. doi:10.18295/2075-0528.2848.
Vancouver
Al-Maqrashi N, Al Busaidi S, Al Rasbi S, Al Alawi AM, Al-Maqbali JS. Effect of Magnesium Supplements on Improving Glucose Control, Blood Pressure and Lipid Profile in Patients With Type 2 Diabetes Mellitus: A systematic review and meta-analysis. Sultan Qaboos University Medical Journal. 2025;25(1):382-394. doi:10.18295/2075-0528.2848
IEEE
N. Al-Maqrashi, S. Al Busaidi, S. Al Rasbi, A. M. Al Alawi, and J. S. Al-Maqbali, "Effect of Magnesium Supplements on Improving Glucose Control, Blood Pressure and Lipid Profile in Patients With Type 2 Diabetes Mellitus: A systematic review and meta-analysis," Sultan Qaboos University Medical Journal, vol. 25, no. 1, pp. 382-394, 2025, doi: 10.18295/2075-0528.2848.