Abstract
Objectives: The Rajan’s heart failure (R-hf) score was proposed to aid risk stratification in heart failure patients. The aim of this study was to validate R-hf risk score in patients with acute decompensated heart failure. Methods: R-hf risk score is derived from the product estimated glomerular filtration rate (mL/min), left ventricular ejection fraction (%), and hemoglobin levels (g/dL) divided by N-terminal pro-brain natriuretic peptide (pg/mL). This was a multinational, multicenter, prospective registry of heart failure from seven countries in the Middle East. Univariable and multivariable logistic regression was applied. Results: A total of 776 patients (mean age = 62.0±14.0 years, 62.4% males; mean left ventricular ejection fraction = 33.0±14.0%) were included. Of these, 459 (59.1%) presented with acute decompensated chronic heart failure. The R-hf risk score group (≤ 5) was marginally associated with a higher risk of all-cause cumulative mortality at three months (adjusted odds ratio (aOR) = 4.28; 95% CI: 0.90–20.30; p = 0.067) and significantly at 12 months (aOR = 3.84; 95% CI: 1.23–12.00; p = 0.021) when compared to those with the highest R score group (≥ 50). Conclusions: Lower R-hf risk scores are associated with increased risk of all-cause cumulative mortality at three and 12 months.
Keywords
Publication details
- DOI
- 10.5001/omj.2023.89
- Journal
- Oman Medical Journal
- Publisher
- Oman Medical Specialty Board
- Open access
- Gold open access
Cite this article
APA 7
Rajan, R., Al Jarallah, M., Al-Zakwani, I., Dashti, R., Sulaiman, K., Panduranga, P., Brady, P. A., & Kobalava, Z. (2023). Development and Validation of R-hf Risk Score in Acute Heart Failure Patients in the Middle East. Oman Medical Journal. https://doi.org/10.5001/omj.2023.89
MLA 9
Rajan, Rajesh, et al. "Development and Validation of R-hf Risk Score in Acute Heart Failure Patients in the Middle East." Oman Medical Journal, 2023. https://doi.org/10.5001/omj.2023.89.
Chicago (author–date)
Rajan, Rajesh, Mohammed Al Jarallah, Ibrahim Al-Zakwani, Raja Dashti, Kadhim Sulaiman, Prashanth Panduranga, Peter A Brady, and Zhanna Kobalava. 2023. "Development and Validation of R-hf Risk Score in Acute Heart Failure Patients in the Middle East." Oman Medical Journal. https://doi.org/10.5001/omj.2023.89.
Harvard
Rajan, R., Al Jarallah, M., Al-Zakwani, I., Dashti, R., Sulaiman, K., Panduranga, P., Brady, P. A. and Kobalava, Z. (2023) 'Development and Validation of R-hf Risk Score in Acute Heart Failure Patients in the Middle East', Oman Medical Journal. doi:10.5001/omj.2023.89.
Vancouver
Rajan R, Al Jarallah M, Al-Zakwani I, Dashti R, Sulaiman K, Panduranga P, et al. Development and Validation of R-hf Risk Score in Acute Heart Failure Patients in the Middle East. Oman Medical Journal. 2023. doi:10.5001/omj.2023.89
IEEE
R. Rajan, M. Al Jarallah, I. Al-Zakwani, R. Dashti, K. Sulaiman, P. Panduranga, P. A. Brady, and Z. Kobalava, "Development and Validation of R-hf Risk Score in Acute Heart Failure Patients in the Middle East," Oman Medical Journal, 2023, doi: 10.5001/omj.2023.89.