Abstract
The authors present a retrospective analysis of three cases of isolated corneal ocular surface squamous neoplasia (C-OSSN) without limbal or conjunctival involvement and review the clinical and anterior segment optical coherence tomography (AS-OCT) features, along with treatment outcomes. The mean age at presentation was 51 years (range: 32-64 years). The mean tumor diameter was 5 mm (range: 3-6.5 mm). All lesions were placoid with <1 mm thickness. One case had surface keratin. AS-OCT revealed hyperreflective epithelium with abrupt transition in all cases, with mean thickness of 118 μm (range: 60-162 μm). One patient underwent alcohol-assisted keratoepitheliectomy (AKE) and two patients received topical Interferon alpha-2B followed by AKE. Histopathology revealed mild squamous dysplasia in all. No tumor residue or recurrence was noted at a mean follow-up period of 2 years (range: 1-4 years). Isolated C-OSSN is rare. AS-OCT serves as a useful noninvasive tool for supporting the diagnosis of AKE yielding long-term favorable outcomes.
Keywords
Publication details
- DOI
- 10.4103/ojo.ojo_111_23
- Journal
- Oman Journal of Ophthalmology, 17(2), 249-253
- Publisher
- Medknow Publications
- Open access
- Gold open access
Cite this article
APA 7
Agarwal, A., Farhan, M. H., Mishra, D. K., & Kaliki, S. (2024). Corneal ocular surface squamous neoplasia: Case series and review of literature. Oman Journal of Ophthalmology, 17(2), 249-253. https://doi.org/10.4103/ojo.ojo_111_23
MLA 9
Agarwal, Ayushi, et al. "Corneal ocular surface squamous neoplasia: Case series and review of literature." Oman Journal of Ophthalmology, vol. 17, no. 2, 2024, pp. 249-253. https://doi.org/10.4103/ojo.ojo_111_23.
Chicago (author–date)
Agarwal, Ayushi, Marwan H Farhan, Dilip K Mishra, and Swathi Kaliki. 2024. "Corneal ocular surface squamous neoplasia: Case series and review of literature." Oman Journal of Ophthalmology 17 (2): 249-253. https://doi.org/10.4103/ojo.ojo_111_23.
Harvard
Agarwal, A., Farhan, M. H., Mishra, D. K. and Kaliki, S. (2024) 'Corneal ocular surface squamous neoplasia: Case series and review of literature', Oman Journal of Ophthalmology, 17(2), pp. 249-253. doi:10.4103/ojo.ojo_111_23.
Vancouver
Agarwal A, Farhan MH, Mishra DK, Kaliki S. Corneal ocular surface squamous neoplasia: Case series and review of literature. Oman Journal of Ophthalmology. 2024;17(2):249-253. doi:10.4103/ojo.ojo_111_23
IEEE
A. Agarwal, M. H. Farhan, D. K. Mishra, and S. Kaliki, "Corneal ocular surface squamous neoplasia: Case series and review of literature," Oman Journal of Ophthalmology, vol. 17, no. 2, pp. 249-253, 2024, doi: 10.4103/ojo.ojo_111_23.