Abstract

The aim is to report corneal melting following intrastromal injection of antivascular endothelial growth factor (anti-VEGF), bevacizumab, for pre-existing corneal neovascularization. A 68-year-old male with a history of failed bilateral penetrating keratoplasties due to scarring from childhood measles and trachoma underwent right eye superficial keratectomy, intrastromal bevacizumab, and amniotic membrane transplant to control the neovascularization in an overseas center. A week later developed corneal melting. In conclusion, anti-VEGF can be used in controlling corneal neovascularization, albeit, is associated with risks such as delayed epithelial healing and corneal melting, particularly in those with limbal stem cell deficiency.

Keywords

Publication details

DOI
10.4103/ojo.ojo_344_24
Journal
Oman Journal of Ophthalmology, 18(2), 205-207
Publisher
Medknow Publications
Open access
Gold open access

Cite this article

APA 7

Al-Ruhaili, M. S., & Al-Mahrouqi, H. H. (2025). Corneal melting following intrastromal injection of bevacizumab for corneal neovascularization. Oman Journal of Ophthalmology, 18(2), 205-207. https://doi.org/10.4103/ojo.ojo_344_24

MLA 9

Al-Ruhaili, Muna Salim, and Haitham Hilal Al-Mahrouqi. "Corneal melting following intrastromal injection of bevacizumab for corneal neovascularization." Oman Journal of Ophthalmology, vol. 18, no. 2, 2025, pp. 205-207. https://doi.org/10.4103/ojo.ojo_344_24.

Chicago (author–date)

Al-Ruhaili, Muna Salim, and Haitham Hilal Al-Mahrouqi. 2025. "Corneal melting following intrastromal injection of bevacizumab for corneal neovascularization." Oman Journal of Ophthalmology 18 (2): 205-207. https://doi.org/10.4103/ojo.ojo_344_24.

Harvard

Al-Ruhaili, M. S. and Al-Mahrouqi, H. H. (2025) 'Corneal melting following intrastromal injection of bevacizumab for corneal neovascularization', Oman Journal of Ophthalmology, 18(2), pp. 205-207. doi:10.4103/ojo.ojo_344_24.

Vancouver

Al-Ruhaili MS, Al-Mahrouqi HH. Corneal melting following intrastromal injection of bevacizumab for corneal neovascularization. Oman Journal of Ophthalmology. 2025;18(2):205-207. doi:10.4103/ojo.ojo_344_24

IEEE

M. S. Al-Ruhaili, and H. H. Al-Mahrouqi, "Corneal melting following intrastromal injection of bevacizumab for corneal neovascularization," Oman Journal of Ophthalmology, vol. 18, no. 2, pp. 205-207, 2025, doi: 10.4103/ojo.ojo_344_24.