Abstract
Intracortical motor decoders degrade across sessions because the set of recorded units changes and persisting units can alter how their firing relates to behavior. Most existing methods update network weights on each new session or rely on unlabeled activity, which does not directly reveal such changes. We present APST, an Association Profile-conditioned Set-Temporal transformer that adapts to new sessions with all network weights frozen. From a few labeled calibration trials, APST summarizes how each unit's firing relates to behavior in a four-dimensional association profile computed in closed form. The profiles condition a set-attention encoder that accepts any number and order of units, followed by a causal transformer for streaming decoding. On held-out DANDI688 sessions from two monkeys, APST reaches velocity $R^2$ of $0.78$ and $0.81$, versus $0.40$ and $0.58$ for a variant that uses neural activity alone, and matches or exceeds an RNN fine-tuned on the same trials. On FALCON private held-out evaluation, it attains $R^2$ of $0.65$, $0.42$, and $0.44$ on M1, M2, and H1.
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- Green open access
Cite this article
APA 7
Zhang, X., Mo, H., Wen, P., Liang, S., Yang, J., Zeng, Y., Wang, Z., & Wang, H. (2026). Association profile conditioning in a set-temporal transformer for cross-session intracortical motor decoding. https://omanscience.com/en/articles/association-profile-conditioning-in-a-set-temporal-transformer-for-cross-session-intracortical-motor-decoding
MLA 9
Zhang, Xinyuan, et al. "Association profile conditioning in a set-temporal transformer for cross-session intracortical motor decoding." https://omanscience.com/en/articles/association-profile-conditioning-in-a-set-temporal-transformer-for-cross-session-intracortical-motor-decoding.
Chicago (author–date)
Zhang, Xinyuan, Handong Mo, Pengfei Wen, Shuang Liang, Jichang Yang, Yan Zeng, Zhongrui Wang, and Han Wang. 2026. "Association profile conditioning in a set-temporal transformer for cross-session intracortical motor decoding." https://omanscience.com/en/articles/association-profile-conditioning-in-a-set-temporal-transformer-for-cross-session-intracortical-motor-decoding.
Harvard
Zhang, X., Mo, H., Wen, P., Liang, S., Yang, J., Zeng, Y., Wang, Z. and Wang, H. (2026) 'Association profile conditioning in a set-temporal transformer for cross-session intracortical motor decoding', Available at: https://omanscience.com/en/articles/association-profile-conditioning-in-a-set-temporal-transformer-for-cross-session-intracortical-motor-decoding.
Vancouver
Zhang X, Mo H, Wen P, Liang S, Yang J, Zeng Y, et al. Association profile conditioning in a set-temporal transformer for cross-session intracortical motor decoding. https://omanscience.com/en/articles/association-profile-conditioning-in-a-set-temporal-transformer-for-cross-session-intracortical-motor-decoding
IEEE
X. Zhang, H. Mo, P. Wen, S. Liang, J. Yang, Y. Zeng, Z. Wang, and H. Wang, "Association profile conditioning in a set-temporal transformer for cross-session intracortical motor decoding," https://omanscience.com/en/articles/association-profile-conditioning-in-a-set-temporal-transformer-for-cross-session-intracortical-motor-decoding.