Abstract
Dabigatran etexilate is a recently approved direct thrombin inhibitor (DTI), which is superior to warfarin in the prevention of stroke and systemic embolism in patients with atrial fibrillation (AF). However, dabigatran use is associated with an increased risk of myocardial infarction (MI) compared to warfarin. The mechanisms for this association effect remain speculative. We present a case of an acute MI and cardiac arrest in a patient with chronic AF who had been recently switched from warfarin to dabigatran. Urgent coronary angiography, at St. Michael’s hospital (Toronto, Canada), revealed evidence of thromboembolism to the distal posterior descending artery. The patient was treated medically and switched back from dabigatran to warfarin. He did well and was discharged after an uneventful stay in the coronary care unit.
Keywords
Publication details
- DOI
- 10.5001/omj.2015.10
- Journal
- Oman Medical Journal
- Publisher
- Oman Medical Specialty Board
- Open access
- Gold open access
Cite this article
APA 7
Abuzeid, W., Al-Lawati, H., & Fam, N. (2015). Acute Myocardial Infarction after Switching from Warfarin to Dabigatran. Oman Medical Journal. https://doi.org/10.5001/omj.2015.10
MLA 9
Abuzeid, Wael, et al. "Acute Myocardial Infarction after Switching from Warfarin to Dabigatran." Oman Medical Journal, 2015. https://doi.org/10.5001/omj.2015.10.
Chicago (author–date)
Abuzeid, Wael, Hatim Al-Lawati, and Neil Fam. 2015. "Acute Myocardial Infarction after Switching from Warfarin to Dabigatran." Oman Medical Journal. https://doi.org/10.5001/omj.2015.10.
Harvard
Abuzeid, W., Al-Lawati, H. and Fam, N. (2015) 'Acute Myocardial Infarction after Switching from Warfarin to Dabigatran', Oman Medical Journal. doi:10.5001/omj.2015.10.
Vancouver
Abuzeid W, Al-Lawati H, Fam N. Acute Myocardial Infarction after Switching from Warfarin to Dabigatran. Oman Medical Journal. 2015. doi:10.5001/omj.2015.10
IEEE
W. Abuzeid, H. Al-Lawati, and N. Fam, "Acute Myocardial Infarction after Switching from Warfarin to Dabigatran," Oman Medical Journal, 2015, doi: 10.5001/omj.2015.10.