المقالات العلمية

Successful Management of NPM1-Mutated Acute Myeloid Leukemia in a Patient with Robinow Syndrome

Appropriate Antiviral Therapy can Prevent Hepatitis B Reactivation and Progression in Chronic Myeloid Leukemia on Therapy with Tyrosine Kinase Inhibitors

Antiviral Therapy and Hepatitis B Reactivation Outcomes in Chronic Myeloid Leukemia Treated with Tyrosine Kinase Inhibitors: A Retrospective Cohort Study

… with potentially fatal complications. We aimed to assess hepatitis reactivation in patients with chronic myeloid leukemia (CML) treated with TKIs. Methods: We retrospectively reviewed the clinical and laboratory records, including antiviral therapy and hepatitis testing data, of CML patients treated with TKI at Sultan …

Acute myeloid leukemia presenting as bilateral proptosis and right temporal swelling

Chronic myeloid leukemia versus acute myeloid leukemia in patients with retinoblastoma

A rare presentation of bilateral ophthalmic relapse of pediatric chronic myeloid leukemia: Multimodal imaging and treatment

Chronic myeloid leukemia (CML) rarely presents under 15 years of age, and its incidence is as low as 2% of all leukemia. Ophthalmic manifestations often present either initially with the diagnosis or as a sign of relapse after remission. The recommended treatment is systemic chemotherapy, intrathecal chemotherapy, ocul …

Evaluation of visual evoked potential in chronic myeloid leukemias

Background: Visual complaint is not very uncommon in chronic myeloid leukemia (CML) patients. Our study aims to evaluate the visual pathway using visual evoked potential (VEP) in cases of CML at the time of diagnosis and 6 weeks after tyrosine kinase therapy, to find out treatment impact in asymptomatic as well as symp …

Bilateral leopard-spot retinopathy as late-onset finding in chronic myeloid leukemia

Newly Diagnosed Acute Myeloid Leukemia with Neck Swelling

Chronic Myeloid Leukaemia: A paradigm for malignancy or just a strange disease?

Chronic myeloid leukaemia (CML), previously a fatal illness, is now readily manageable with oral medication. First described in the 1840s, there was no widely accepted cure until the advent of allogeneic stem cell transplantation in the late 1970s. This treatment was of limited value because of donor availability and t …

Impact of Comorbidities on Survival Among Patients with Chronic Myeloid Leukaemia Using the Charlson Comorbidity Index: Retrospective study from Basra, Iraq

… Charlson Comorbidity Index (CCI) to examine the effect of comorbidities on OS among patients with chronic myeloid leukaemia (CML) treated with tyrosine kinase inhibitors. Methods: This retrospective study was conducted between January 2006 and October 2016 and included 247 CML patients treated at the Basra Oncology & H …

IL-6 Induces CD45 Expression on Myeloid Cells

… ctives: Activation of IL-6 facilitates CD45 expression in myeloma cells, but little has been reported for myeloid malignancies. This study aimed to investigate whether IL-6 enhances CD45 expression on myeloid malignancies and whether myeloid cells are dependent on IL-6 activation to express CD45 on their cell membrane. …