The effect of group quality of life therapy on hope and health-related quality of life in patients with major depressive disorder: A randomized controlled trial

الملخص

BACKGROUND: Major depressive disorder (MDD) significantly impacts individuals’ functioning by detrimentally influencing both their mental and physical well-being, consequently affecting their overall quality of life. This study aims to assess the impact of quality of life therapy (QOLT) on hope and health-related quality of life (HRQoL) among patients with MDD. MATERIALS AND METHODS: This randomized clinical trial involved 56 patients with MDD who sought treatment at psychiatry clinics in Iran during the year 2022. Participants were selected through convenience sampling and subsequently assigned to control and intervention groups using a random blocked allocation method. Before the intervention, all patients completed the World Health Organization Quality of Life questionnaire and Snyder’s hope scale as part of a pretest. The intervention group underwent a 10-week QOLT program, consisting of weekly 90-min sessions. Following the intervention, both control and intervention groups completed posttests by re-evaluating the research questionnaires. The collected data were analyzed using Statistical Package for the Social Sciences software version 26, employing independent two-sample t -tests and paired t -tests. RESULTS: Before the intervention, the two groups did not exhibit significant differences in demographic variables, HRQoL, and hopefulness ( P > 0.05). However, after the intervention, significant differences emerged between the groups in terms of HRQoL and hopefulness ( P < 0.05). Conversely, the control group showed no significant changes throughout the study period ( P > 0.05). CONCLUSION: This study showed that QOLT effectively improves HRQoL and hopefulness in patients with MDD. Consequently, QOLT can be considered as an impactful intervention for enhancing both HRQoL and hopefulness among patients with MDD.

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