الملخص
Objectives: Haemolytic disease of the fetus and newborn (HDFN) causes hydrops fetalis. The successful treatment of HDFN has been reported with intrauterine blood transfusion (IUT). This study aimed to describe the initial experience with IUT procedures in Oman. Methods: This retrospective observational study took place at the Royal Hospital and Sultan Qaboos University Hospital Blood Bank, Muscat, Oman, and included all women who underwent IUT procedures in Oman between March 2012 and March 2016. Gestational and neonatal outcomes were assessed, including complications, morbidity, neurodevelopmental sequelae and mortality. Results: A total of 28 IUT procedures for 13 fetuses carried by 11 women were performed. Gestational age at the time of referral ranged from 13–30 weeks, while the median gestational age at first IUT procedure was 26 weeks (range: 19–30 weeks). Indications for the procedure included HDFN caused by anti-D (n = 6), a combination of anti-D and anti-C (n = 4), anti-K (n = 1) and anti-Jsb (n = 1) antibodies and nonimmune hydrops fetalis due to a congenital parvovirus infection (n = 1). Median fetal haemoglobin levels at the beginning and end of the procedure were 4.6 g/dL and 12.8 g/dL, respectively. Most procedures were transplacental intravascular transfusions through the placental umbilical cord root (71.4%), followed by transamniotic intravascular transfusions (14.3%). The overall survival rate was 61.5%, with five deaths; of these, four were intrauterine and one was an early neonatal death due to non-resolved hydrops and severe cardiac dysfunction. Conclusion: As a relatively novel obstetric procedure in Oman, IUT seems to result in a favourable outcome for hydropic fetuses.
بيانات النشر
- المعرّف الرقمي
- 10.18295/squmj.2018.18.01.006
- المجلة
- مجلة جامعة السلطان قابوس الطبية, 18(1), e34-42
- الناشر
- جامعة السلطان قابوس
- وصول مفتوح
- وصول مفتوح ذهبي
- الترخيص
- CC BY-ND 4.0
اقتبس هذه المقالة
APA 7
Al-Riyami, A. Z., Al-Salmani, M., Al-Mahrooqi, S. N., Sabah, Al-Marhoobi, A., Al-Hinai, S., Al-Hosni, S., Panchatcharam, S. M., & Al-Arimi, Z. A. (2025). Intrauterine Fetal Blood Transfusion: Descriptive study of the first four years’ experience in Oman. Sultan Qaboos University Medical Journal, 18(1), e34-42. https://doi.org/10.18295/squmj.2018.18.01.006
MLA 9
Al-Riyami, Arwa Z., et al. "Intrauterine Fetal Blood Transfusion: Descriptive study of the first four years’ experience in Oman." Sultan Qaboos University Medical Journal, vol. 18, no. 1, 2025, pp. e34-42. https://doi.org/10.18295/squmj.2018.18.01.006.
شيكاغو (المؤلف–التاريخ)
Al-Riyami, Arwa Z., Mouza Al-Salmani, Sabria N. Al-Mahrooqi, Sabah, Ali Al-Marhoobi, Sumaiya Al-Hinai, Saif Al-Hosni, Sathiya M. Panchatcharam, and Zainab A. Al-Arimi. 2025. "Intrauterine Fetal Blood Transfusion: Descriptive study of the first four years’ experience in Oman." Sultan Qaboos University Medical Journal 18 (1): e34-42. https://doi.org/10.18295/squmj.2018.18.01.006.
هارفارد
Al-Riyami, A. Z., Al-Salmani, M., Al-Mahrooqi, S. N., Sabah, Al-Marhoobi, A., Al-Hinai, S., Al-Hosni, S., Panchatcharam, S. M. and Al-Arimi, Z. A. (2025) 'Intrauterine Fetal Blood Transfusion: Descriptive study of the first four years’ experience in Oman', Sultan Qaboos University Medical Journal, 18(1), pp. e34-42. doi:10.18295/squmj.2018.18.01.006.
فانكوفر
Al-Riyami AZ, Al-Salmani M, Al-Mahrooqi SN, Sabah, Al-Marhoobi A, Al-Hinai S, et al. Intrauterine Fetal Blood Transfusion: Descriptive study of the first four years’ experience in Oman. Sultan Qaboos University Medical Journal. 2025;18(1):e34-42. doi:10.18295/squmj.2018.18.01.006
IEEE
A. Z. Al-Riyami, M. Al-Salmani, S. N. Al-Mahrooqi, Sabah, A. Al-Marhoobi, S. Al-Hinai, S. Al-Hosni, S. M. Panchatcharam, and Z. A. Al-Arimi, "Intrauterine Fetal Blood Transfusion: Descriptive study of the first four years’ experience in Oman," Sultan Qaboos University Medical Journal, vol. 18, no. 1, pp. e34-42, 2025, doi: 10.18295/squmj.2018.18.01.006.