الملخص
Guillain-Barré syndrome (GBS) is a recognised complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We report two children with GBS associated with SARS-CoV-2 who presented to a tertiary centre in Muscat, Oman in 2021: The first patient was a three-month-old female infant who presented with bradypnea, encephalopathy, and generalised weakness that required mechanical ventilation. Polymerase chain reaction (PCR) testing of the nasopharyngeal swabs (NPS) was positive for SARS-CoV-2. She had axonal variant GBS based on a nerve conduction study, cerebrospinal fluid analysis, and neuroimaging findings. The second patient was a six-year-old girl with fever, vomiting, and diarrhea followed by ascending weakness who presented with quadriplegia and facial weakness. Subsequently, she developed respiratory muscle weakness and required mechanical ventilation. PCR testing of NPS was negative for SARS-Cov-2, however IgG serology analysis was positive. The clinical course of these two patients was rapidly progressive and both of them required mechanical ventilation. The patient with axonal variant GBS made an incomplete recovery.
بيانات النشر
- المعرّف الرقمي
- 10.18295/squmj.5.2022.040
- المجلة
- مجلة جامعة السلطان قابوس الطبية, 23(3), 400-404
- الناشر
- جامعة السلطان قابوس
- وصول مفتوح
- وصول مفتوح ذهبي
- الترخيص
- CC BY-ND 4.0
اقتبس هذه المقالة
APA 7
Al-Amrani, F., Al-Abdwani, R., Al Rashdi, F., Al Ajmi, E., & Al-Futaisi, A. (2025). Guillain-Barré Syndrome Associated with SARS-CoV-2 in Two Pediatric Patients. Sultan Qaboos University Medical Journal, 23(3), 400-404. https://doi.org/10.18295/squmj.5.2022.040
MLA 9
Al-Amrani, Fatema, et al. "Guillain-Barré Syndrome Associated with SARS-CoV-2 in Two Pediatric Patients." Sultan Qaboos University Medical Journal, vol. 23, no. 3, 2025, pp. 400-404. https://doi.org/10.18295/squmj.5.2022.040.
شيكاغو (المؤلف–التاريخ)
Al-Amrani, Fatema, Raghad Al-Abdwani, Fatma Al Rashdi, Eiman Al Ajmi, and Amna Al-Futaisi. 2025. "Guillain-Barré Syndrome Associated with SARS-CoV-2 in Two Pediatric Patients." Sultan Qaboos University Medical Journal 23 (3): 400-404. https://doi.org/10.18295/squmj.5.2022.040.
هارفارد
Al-Amrani, F., Al-Abdwani, R., Al Rashdi, F., Al Ajmi, E. and Al-Futaisi, A. (2025) 'Guillain-Barré Syndrome Associated with SARS-CoV-2 in Two Pediatric Patients', Sultan Qaboos University Medical Journal, 23(3), pp. 400-404. doi:10.18295/squmj.5.2022.040.
فانكوفر
Al-Amrani F, Al-Abdwani R, Al Rashdi F, Al Ajmi E, Al-Futaisi A. Guillain-Barré Syndrome Associated with SARS-CoV-2 in Two Pediatric Patients. Sultan Qaboos University Medical Journal. 2025;23(3):400-404. doi:10.18295/squmj.5.2022.040
IEEE
F. Al-Amrani, R. Al-Abdwani, F. Al Rashdi, E. Al Ajmi, and A. Al-Futaisi, "Guillain-Barré Syndrome Associated with SARS-CoV-2 in Two Pediatric Patients," Sultan Qaboos University Medical Journal, vol. 23, no. 3, pp. 400-404, 2025, doi: 10.18295/squmj.5.2022.040.