الملخص
Background: To analyze changes over a 3-year period in ganglion cell complex (GCC) thickness in individuals with type 1 diabetes mellitus (T1DM) using spectral-domain optical coherence tomography (Optovue, Fremont, CA, USA). Methods: Thirty-seven individuals from "Friends for Life Conference" with T1DM and a 3-year history of GCC thickness measurements were included in the study. Data analysis using SPSS 22 and Excel StatPlus was completed to note the subgroups that had a significant change. Results: Significant decreases were noted in the following subgroups with slope in parenthesis. Overall: GCC superior thickness OD (-0.48)Male: GCC thickness OD (-0.86), GCC superior thickness OD (-0.735)Body mass index (BMI) 25.0-29.9: GCC thickness OD (-0.48), GCC superior thickness OS (-0.915), GCC inferior thickness OD (-0.43)Ages 10-20 years: GCC superior thickness OD (-0.635)Duration of diabetes 10-20 years: GCC thickness OD (-1.055), GCC superior thickness OD (-0.99). Conclusion: GCC loss was noted in individuals who were males, those with BMIs of 25.0-29.9, and those who had diabetes for 10-20 years. Ganglion cell loss was also noted before the presence of any diabetic retinopathy, suggesting onset of neuronal loss before any vasculature changes.
الكلمات المفتاحية
بيانات النشر
- المعرّف الرقمي
- 10.4103/ojo.ojo_224_2017
- المجلة
- المجلة العُمانية لطب العيون, 12(1), 31-36
- الناشر
- منشورات ميدنو
- وصول مفتوح
- وصول مفتوح ذهبي
اقتبس هذه المقالة
APA 7
Thangamathesvaran, L., Kommana, S. S., Duong, K., Szirth, B., & Khouri, A. S. (2019). Ganglion cell complex loss in patients with type 1 diabetes: A 36-month retrospective study. Oman Journal of Ophthalmology, 12(1), 31-36. https://doi.org/10.4103/ojo.ojo_224_2017
MLA 9
Thangamathesvaran, Loka, et al. "Ganglion cell complex loss in patients with type 1 diabetes: A 36-month retrospective study." Oman Journal of Ophthalmology, vol. 12, no. 1, 2019, pp. 31-36. https://doi.org/10.4103/ojo.ojo_224_2017.
شيكاغو (المؤلف–التاريخ)
Thangamathesvaran, Loka, Sumana S Kommana, Kim Duong, Bernard Szirth, and Albert S Khouri. 2019. "Ganglion cell complex loss in patients with type 1 diabetes: A 36-month retrospective study." Oman Journal of Ophthalmology 12 (1): 31-36. https://doi.org/10.4103/ojo.ojo_224_2017.
هارفارد
Thangamathesvaran, L., Kommana, S. S., Duong, K., Szirth, B. and Khouri, A. S. (2019) 'Ganglion cell complex loss in patients with type 1 diabetes: A 36-month retrospective study', Oman Journal of Ophthalmology, 12(1), pp. 31-36. doi:10.4103/ojo.ojo_224_2017.
فانكوفر
Thangamathesvaran L, Kommana SS, Duong K, Szirth B, Khouri AS. Ganglion cell complex loss in patients with type 1 diabetes: A 36-month retrospective study. Oman Journal of Ophthalmology. 2019;12(1):31-36. doi:10.4103/ojo.ojo_224_2017
IEEE
L. Thangamathesvaran, S. S. Kommana, K. Duong, B. Szirth, and A. S. Khouri, "Ganglion cell complex loss in patients with type 1 diabetes: A 36-month retrospective study," Oman Journal of Ophthalmology, vol. 12, no. 1, pp. 31-36, 2019, doi: 10.4103/ojo.ojo_224_2017.