الملخص
Objectives: This study aimed to determine associations between hypothyroidism during pregnancy and selected maternal and neonatal outcomes. Methods: A retrospective, cohort study was conducted between January 2018 and December 2020 at the two main tertiary hospitals in Muscat, Oman. The study included 408 Omani pregnant women aged 18–45 years. Participants were divided into two groups: those diagnosed with overt or subclinical hypothyroidism (n = 201; exposed group) and those with normal thyroid function (n = 207; unexposed group), matched for relevant variables. Data were collected from electronic medical records to assess maternal and neonatal outcomes. Results: Most exposed women (94.5%) had overt hypothyroidism. No significant differences were observed between the two groups in gestational diabetes mellitus, gestational hypertension, or pre-eclampsia (P >0.05). Women with hypothyroidism had a significantly higher risk of iron deficiency anaemia at delivery (relative risk: 2.22, 95% confidence interval: 1.68–2.94; P = 0.05). Conclusion: Hypothyroidism during pregnancy was not associated with an increased risk of most adverse maternal or neonatal outcomes in this cohort. This may be attributed to the effective management of hypothyroidism, as the majority of affected women were on thyroxine therapy, maintaining a clinically and biochemically euthyroid state throughout pregnancy.
بيانات النشر
- المعرّف الرقمي
- 10.18295/2075-0528.2966
- المجلة
- مجلة جامعة السلطان قابوس الطبية, 26(1), 129-138
- الناشر
- جامعة السلطان قابوس
- وصول مفتوح
- وصول مفتوح ذهبي
- الترخيص
- CC BY-ND 4.0
اقتبس هذه المقالة
APA 7
Al Kindi, R., Al Ghammari, N., Al Malki, A., Al Ismaili, A., & Al Sumri, H. (2026). Associations Between Overt and Subclinical Hypothyroidism in Pregnancy and Adverse Maternal and Neonatal Outcomes: A cohort study. Sultan Qaboos University Medical Journal, 26(1), 129-138. https://doi.org/10.18295/2075-0528.2966
MLA 9
Al Kindi, Rahma, et al. "Associations Between Overt and Subclinical Hypothyroidism in Pregnancy and Adverse Maternal and Neonatal Outcomes: A cohort study." Sultan Qaboos University Medical Journal, vol. 26, no. 1, 2026, pp. 129-138. https://doi.org/10.18295/2075-0528.2966.
شيكاغو (المؤلف–التاريخ)
Al Kindi, Rahma, Noof Al Ghammari, Amina Al Malki, Aida Al Ismaili, and Hana Al Sumri. 2026. "Associations Between Overt and Subclinical Hypothyroidism in Pregnancy and Adverse Maternal and Neonatal Outcomes: A cohort study." Sultan Qaboos University Medical Journal 26 (1): 129-138. https://doi.org/10.18295/2075-0528.2966.
هارفارد
Al Kindi, R., Al Ghammari, N., Al Malki, A., Al Ismaili, A. and Al Sumri, H. (2026) 'Associations Between Overt and Subclinical Hypothyroidism in Pregnancy and Adverse Maternal and Neonatal Outcomes: A cohort study', Sultan Qaboos University Medical Journal, 26(1), pp. 129-138. doi:10.18295/2075-0528.2966.
فانكوفر
Al Kindi R, Al Ghammari N, Al Malki A, Al Ismaili A, Al Sumri H. Associations Between Overt and Subclinical Hypothyroidism in Pregnancy and Adverse Maternal and Neonatal Outcomes: A cohort study. Sultan Qaboos University Medical Journal. 2026;26(1):129-138. doi:10.18295/2075-0528.2966
IEEE
R. Al Kindi, N. Al Ghammari, A. Al Malki, A. Al Ismaili, and H. Al Sumri, "Associations Between Overt and Subclinical Hypothyroidism in Pregnancy and Adverse Maternal and Neonatal Outcomes: A cohort study," Sultan Qaboos University Medical Journal, vol. 26, no. 1, pp. 129-138, 2026, doi: 10.18295/2075-0528.2966.