الملخص
Background: Breast cancer is among the most common malignancies in women around the world. There is evidence of high prevalence of serum/blood Vitamin D deficiency in Iranian women. Considering the multitude of factors that may be involved in the prognosis and lifespan of breast cancer patients, this study investigated the level of Vitamin D in Iranian patients with nonmetastatic breast cancer. Materials and Methods: This cross-sectional study was carried out on 214 women diagnosed with breast cancer, who were referred to the radio-oncology department. Serum Vitamin D level of the patients was measured. Prognostic factors were determined based on demographic and pathological characteristics. The results were analyzed using descriptive statistics tests, Chi-square, one-way analysis of variance, Kaplan–Meier, and Cox regression model in SPSS v22. For all cases, the significance level was considered to be P < 0.05. Results: The total mean of 25-hydroxyvitamin D serum level was 25.15 ± 17.68 ng/ml. There was no significant relationship between levels of Vitamin D with disease stage, tumor size, tumor grade, estrogen receptor, progesterone receptor, and Human epidermal growth factor receptor 2 ( P > 0.05). The mean survival time was 5 years and 45 days. Conclusion: No relationship was found between serum Vitamin D levels and the factors affecting the prognosis of nonmetastatic breast cancer. The Cox analysis showed that the survival time was not influenced by Vitamin D as a prognosis factor.
الكلمات المفتاحية
الموضوع
بيانات النشر
- المعرّف الرقمي
- 10.4103/jrms.jrms_951_21
- المجلة
- Journal of Research in Medical Sciences, 27(1), 56
- الناشر
- Wolters Kluwer Medknow Publications
- وصول مفتوح
- وصول مفتوح ذهبي
- الترخيص
- CC BY-NC-SA 4.0
اقتبس هذه المقالة
APA 7
Shahrzad, M. K., Gharehgozlou, R., Fadaei, S., Hajian, P., & Mirzaei, H. R. (2022). Association between serum Vitamin D levels and prognostic factors in nonmetastatic breast cancer patients. Journal of Research in Medical Sciences, 27(1), 56. https://doi.org/10.4103/jrms.jrms_951_21
MLA 9
Shahrzad, Mohammad Karim, et al. "Association between serum Vitamin D levels and prognostic factors in nonmetastatic breast cancer patients." Journal of Research in Medical Sciences, vol. 27, no. 1, 2022, pp. 56. https://doi.org/10.4103/jrms.jrms_951_21.
شيكاغو (المؤلف–التاريخ)
Shahrzad, Mohammad Karim, Reyhaneh Gharehgozlou, Sara Fadaei, Parastoo Hajian, and Hamid Reza Mirzaei. 2022. "Association between serum Vitamin D levels and prognostic factors in nonmetastatic breast cancer patients." Journal of Research in Medical Sciences 27 (1): 56. https://doi.org/10.4103/jrms.jrms_951_21.
هارفارد
Shahrzad, M. K., Gharehgozlou, R., Fadaei, S., Hajian, P. and Mirzaei, H. R. (2022) 'Association between serum Vitamin D levels and prognostic factors in nonmetastatic breast cancer patients', Journal of Research in Medical Sciences, 27(1), pp. 56. doi:10.4103/jrms.jrms_951_21.
فانكوفر
Shahrzad MK, Gharehgozlou R, Fadaei S, Hajian P, Mirzaei HR. Association between serum Vitamin D levels and prognostic factors in nonmetastatic breast cancer patients. Journal of Research in Medical Sciences. 2022;27(1):56. doi:10.4103/jrms.jrms_951_21
IEEE
M. K. Shahrzad, R. Gharehgozlou, S. Fadaei, P. Hajian, and H. R. Mirzaei, "Association between serum Vitamin D levels and prognostic factors in nonmetastatic breast cancer patients," Journal of Research in Medical Sciences, vol. 27, no. 1, pp. 56, 2022, doi: 10.4103/jrms.jrms_951_21.