الملخص
Langerhans cell histiocytosis (LCH) is rarely encountered in ophthalmology practice. It is a spectrum of disorder characterized by accumulation of histiocytes in various tissues. Diagnosis is challenging as it may simulate periorbital hematoma, rhabdomyosarcoma, and neuroblastoma. We report a case of unifocal LCH with orbital extension. Diagnosis was obtained from incisional biopsy, and histopathological examination showed numerous histiocytes with eosinophilic infiltrations. The presence of Langerhans cells was confirmed by the presence of protein S-100, CD1a, and/or Langerin (CD207). Treatment depends on the degree of organ involvement. She responded well to cytotoxic drugs and steroids. This emphasized that prompt tissue diagnosis is crucial for early management.
الكلمات المفتاحية
بيانات النشر
- المعرّف الرقمي
- 10.4103/ojo.ojo_149_2017
- المجلة
- المجلة العُمانية لطب العيون, 11(3), 284-287
- الناشر
- منشورات ميدنو
- وصول مفتوح
- وصول مفتوح ذهبي
اقتبس هذه المقالة
APA 7
Addenan, M., May, C. M., Hooi, T. K., Ismail, F., & Kamalden, T. A. (2018). A rare case of solitary unifocal Langerhans cell histiocytosis with orbital extension: Diagnostic dilemma. Oman Journal of Ophthalmology, 11(3), 284-287. https://doi.org/10.4103/ojo.ojo_149_2017
MLA 9
Addenan, Maftuhim, et al. "A rare case of solitary unifocal Langerhans cell histiocytosis with orbital extension: Diagnostic dilemma." Oman Journal of Ophthalmology, vol. 11, no. 3, 2018, pp. 284-287. https://doi.org/10.4103/ojo.ojo_149_2017.
شيكاغو (المؤلف–التاريخ)
Addenan, Maftuhim, Choo May May, Teoh Kean Hooi, Fazliana Ismail, and Tengku Ain Kamalden. 2018. "A rare case of solitary unifocal Langerhans cell histiocytosis with orbital extension: Diagnostic dilemma." Oman Journal of Ophthalmology 11 (3): 284-287. https://doi.org/10.4103/ojo.ojo_149_2017.
هارفارد
Addenan, M., May, C. M., Hooi, T. K., Ismail, F. and Kamalden, T. A. (2018) 'A rare case of solitary unifocal Langerhans cell histiocytosis with orbital extension: Diagnostic dilemma', Oman Journal of Ophthalmology, 11(3), pp. 284-287. doi:10.4103/ojo.ojo_149_2017.
فانكوفر
Addenan M, May CM, Hooi TK, Ismail F, Kamalden TA. A rare case of solitary unifocal Langerhans cell histiocytosis with orbital extension: Diagnostic dilemma. Oman Journal of Ophthalmology. 2018;11(3):284-287. doi:10.4103/ojo.ojo_149_2017
IEEE
M. Addenan, C. M. May, T. K. Hooi, F. Ismail, and T. A. Kamalden, "A rare case of solitary unifocal Langerhans cell histiocytosis with orbital extension: Diagnostic dilemma," Oman Journal of Ophthalmology, vol. 11, no. 3, pp. 284-287, 2018, doi: 10.4103/ojo.ojo_149_2017.