[
    {
        "id": "osp-11057",
        "type": "article-journal",
        "title": "The p53 Mutation/Deletion Profile in a Small Cohort of the Omani Population with Diffuse Large B-Cell Lymphoma",
        "author": [
            {
                "family": "Tamimi",
                "given": "Yahya"
            },
            {
                "family": "Al-Harthy",
                "given": "Sheikha"
            },
            {
                "family": "Al Kindi",
                "given": "Ibrahim"
            },
            {
                "family": "Mohammed",
                "given": ""
            },
            {
                "family": "Babiker",
                "given": "Hamza"
            },
            {
                "family": "Al-Moundhri",
                "given": "Mansour"
            },
            {
                "family": "Burney",
                "given": "Ikram"
            }
        ],
        "URL": "https://omanscience.com/en/articles/the-p53-mutation-deletion-profile-in-a-small-cohort-of-the-omani-population-with-diffuse-large-b-cell-lymphoma",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2025
                ]
            ]
        },
        "container-title": "Sultan Qaboos University Medical Journal",
        "volume": "14",
        "issue": "1",
        "page": "50-58",
        "DOI": "10.18295/2075-0528.1546",
        "publisher": "Sultan Qaboos University",
        "ISSN": "2075-051X",
        "abstract": "Objectives: Mutations/deletions affecting the TP53 gene are considered an independent marker predicting a poor prognosis for patients with diffuse large B-cell lymphoma (DLBCL). A cohort within a genetically isolated population was investigated for p53 mutation/deletion status. Methods:Deoxyribonucleic acid (DNA) samples were extracted from 23 paraffin-embedded blocks obtained from DLBCL patients, and subjected to polymerase chain reaction (PCR) amplification and sequencing of exons 4–9 of the p53 gene. Results: While 35% of patients analysed displayed allelic deletions (P"
    }
]