[
    {
        "id": "osp-11596",
        "type": "article-journal",
        "title": "Serum Level of Heart-Type Fatty Acid-Binding Protein in Patients with Chronic Renal Failure",
        "author": [
            {
                "family": "Alhadi",
                "given": "Hafidh A."
            },
            {
                "family": "William",
                "given": "Brent"
            },
            {
                "family": "A.",
                "given": "Keith"
            }
        ],
        "URL": "https://omanscience.com/en/articles/serum-level-of-heart-type-fatty-acid-binding-protein-in-patients-with-chronic-renal-failure",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2025
                ]
            ]
        },
        "container-title": "Sultan Qaboos University Medical Journal",
        "volume": "9",
        "issue": "3",
        "page": "311-314",
        "DOI": "10.18295/2075-0528.2806",
        "publisher": "Sultan Qaboos University",
        "ISSN": "2075-051X",
        "abstract": "Objectives: Heart-type fatty acid binding-protein (H-FABP) has been reported to be a potential novel biochemical marker for the early diagnosis of acute myocardial infarction (AMI). The effect of kidney diseases on the renal handling of H-FABP has not yet been fully evaluated. The aim of this study was to compare the effect of renal failure on the level of H-FABP and cardiac troponin (cTnT) concentrations. Methods: The study population was a small group of 16 patients with renal failure (6 females, 10 males aged 30-70 years) on routine regular haemodialysis or peritoneal dialysis. Results: The mean ±SD of serum urea and creatinine concentration in this group of patients was 19 ±9.6 mmol/L and 531.3 ±231.2 mmol/L respectively. H-FABP was increased in all 16 patients (81 ±53.3μg/L). The cTnT was increased ≥ 0.1μg/L in 8 patients (50%), ≥ 0.2μg/L in 5 patients (31.3%), and ≥ 0.3μg/L in 1 patient (6%). Conclusion: The diagnostic efficiency of H-FABP and cTnT for the diagnosis of AMI in the presence of renal failure may be limited and such patients may have high levels even in the absence of AMI."
    }
]