[
    {
        "id": "osp-12863",
        "type": "article-journal",
        "title": "Selective laser trabeculoplasty: Does energy dosage predict response?",
        "author": [
            {
                "family": "Habib",
                "given": "Larissa"
            },
            {
                "family": "Lin",
                "given": "James"
            },
            {
                "family": "Berezina",
                "given": "Tamara"
            },
            {
                "family": "Holland",
                "given": "Bart"
            },
            {
                "family": "Fechtner",
                "given": "Robert D"
            },
            {
                "family": "Khouri",
                "given": "Albert S"
            }
        ],
        "URL": "https://omanscience.com/en/articles/selective-laser-trabeculoplasty-does-energy-dosage-predict-response",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2013
                ]
            ]
        },
        "container-title": "Oman Journal of Ophthalmology",
        "volume": "6",
        "issue": "2",
        "page": "92-95",
        "DOI": "10.4103/0974-620x.116635",
        "publisher": "Medknow Publications",
        "ISSN": "0974-620X",
        "abstract": "Background: Selective laser trabeculoplasty (SLT) is a widely used treatment for open angle glaucoma, producing sustained reductions of intraocular pressure (IOP). The aim of this study was to evaluate the long-term relationship between SLT energy dosage and IOP reduction.\n\nMaterials and methods: A retrospective review was performed for patients receiving primary SLT therapy, with inclusion of subjects treated with 360° of SLT. Energy settings were collected upon treatment and IOP was collected at baseline up to 36 months. Pearson's correlation coefficient was used to determine whether there was a significant correlation between SLT energy and IOP reduction at all time points. Kaplan-Meier analysis with log-rank test was performed to determine the differences in IOP reduction ≥20% from baseline among those treated with low (105 mJ) energy SLT.\n\nResults: A total of 104 eyes (75 patients) were included. The mean total SLT energy was 93.73 mJ (standard deviation (SD) = 21.83 mJ, range: 34.4-122 mJ). A significant positive correlation (P ≤ 0.05) between the amount of energy delivered and IOP reduction was found at all time points. Log-rank test showed a significant difference in IOP reduction ≥20% from baseline between the three energy groups, with low energy patients experiencing failure at an earlier time (P = 0.05).\n\nConclusions: Within the range of total energy examined, there is a positive correlation between total energy used and amount of pressure reduction achieved at up to 3 years of follow-up. This may be useful in determining the optimal energy dosage for maximum effect for patients receiving SLT."
    }
]