[
    {
        "id": "osp-2585",
        "type": "article-journal",
        "title": "RHD Positive Haplotype in D Negative Omani Blood Donor",
        "author": [
            {
                "family": "Al-Lawati",
                "given": "Mujtaba"
            },
            {
                "family": "Al Balushi",
                "given": "Badriya"
            }
        ],
        "URL": "https://omanscience.com/en/articles/rhd-positive-haplotype-in-d-negative-omani-blood-donor",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2023
                ]
            ]
        },
        "container-title": "Oman Medical Journal",
        "DOI": "10.5001/omj.2023.11",
        "publisher": "Oman Medical Specialty Board",
        "ISSN": "1999-768X",
        "abstract": "The frequency of Rhesus D negative blood group in Omanis is 8.35% but the molecular background of this phenotype is unknown in the Omani population. The Rhesus D negative phenotype has a high molecular diversity. We report a rare case of serological D negative with existence of complete RHD gene in a 43-year-old Omani male blood donor. Molecular analysis of RHD exons showed duplication across the boundary of intron 3 and exon 4. This is a 37 bp insert in RHD exon 4 along with c.609 G>A mutation. We are uncertain if the presence of RHDΨ is homozygous (RHDΨ/RHDΨ) or hemizygous (RHDΨ/del). Therefore, molecular basis of D zygosity determination would be a good approach to further explore the case."
    }
]