[
    {
        "id": "osp-2579",
        "type": "article-journal",
        "title": "Prevalence and Genotypes of Hepatitis C Infection Among Hemodialysis Patients in Bushehr, Iran",
        "author": [
            {
                "family": "Taherkhani",
                "given": "Reza"
            },
            {
                "family": "Farshadpour",
                "given": "Fatemeh"
            },
            {
                "family": "Asayesh",
                "given": "Reza"
            }
        ],
        "URL": "https://omanscience.com/en/articles/prevalence-and-genotypes-of-hepatitis-c-infection-among-hemodialysis-patients-in-bushehr-iran",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2023
                ]
            ]
        },
        "container-title": "Oman Medical Journal",
        "DOI": "10.5001/omj.2023.60",
        "publisher": "Oman Medical Specialty Board",
        "ISSN": "1999-768X",
        "abstract": "Objectives: To investigate the prevalence, genotype distribution, and risk factors of hepatitis C virus (HCV) infection among patients undergoing regular hemodialysis in Bushehr province in southern Iran. Methods: All chronic hemodialysis patients from the cities of Dashtestan, Genaveh, and Bushehr participated in this study. Enzyme-linked immunosorbent assay was used to detect anti-HCV antibodies. Molecular detection of HCV infection was performed by semi-nested reverse transcription polymerase chain reaction assay, targeting 5’ untranslated region and core region of the genome, and sequencing. Results: Of 279 hemodialysis patients, 15 (5.4%) were positive for anti-HCV antibodies, and two (0.7%) patients had HCV viremia with genotype 3a. The hemodialysis patients had a significantly higher seroprevalence of HCV than the control group (p = 0.007). Patients with Arab ethnicity had significantly higher anti-HCV seroprevalence compared to those with Fars ethnicity (p = 0.026). Anti-HCV seropositivity was not statistically associated with the patients’ sex, age group, place of residence, level of education, duration of hemodialysis, or history of blood transfusion. Conclusions: Considering the high seroprevalence of HCV in hemodialysis patients, regular screening of these patients for HCV infection and prompt treatment of those found infected are recommended."
    }
]