[
    {
        "id": "osp-1442",
        "type": "article-journal",
        "title": "Prepubertal Hypertransfusion in Thalassemia Intermedia: Sustained Positive Effects on Growth, Splenic Function and Endocrine Parameters",
        "author": [
            {
                "family": "Tony",
                "given": "Surekha"
            },
            {
                "family": "Daar",
                "given": "Shahina"
            },
            {
                "family": "Zachariah",
                "given": "Mathew"
            },
            {
                "family": "Wali",
                "given": "Yasser"
            }
        ],
        "URL": "https://omanscience.com/en/articles/prepubertal-hypertransfusion-in-thalassemia-intermedia-sustained-positive-effects-on-growth-splenic-function-and-endocrine-parameters",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2012
                ]
            ]
        },
        "container-title": "Oman Medical Journal",
        "DOI": "10.5001/omj.2012.125",
        "publisher": "Oman Medical Specialty Board",
        "ISSN": "1999-768X",
        "abstract": "We report a known case of thalassemia intermedia (Hb Dhofar) who in spite of mild thalassemic facies, attained his normal genetic height, pubertal maturity and improved self-image with minimal splenomegaly through a hypertransfusion/chelation regimen that was started just before puberty and maintained for 5 years. As there are no clear guidelines in the management of patients with thalassemia intermedia, the option of hypertransfusion/chelation during the pubertal growth spurt may alleviate some of the complications associated with thalassemia intermedia."
    }
]