[
    {
        "id": "osp-12449",
        "type": "article-journal",
        "title": "Outcomes of preoperative intrapterygial injection of mitomycin C for pterygium excision with and without inferior conjunctival flap",
        "author": [
            {
                "family": "Gupta",
                "given": "Ved Prakash"
            },
            {
                "family": "Sanghi",
                "given": "Shekhar"
            },
            {
                "family": "Rohatgi",
                "given": "Jolly"
            },
            {
                "family": "Dhaliwal",
                "given": "Upreet"
            }
        ],
        "URL": "https://omanscience.com/en/articles/outcomes-of-preoperative-intrapterygial-injection-of-mitomycin-c-for-pterygium-excision-with-and-without-inferior-conjunctival-flap",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2019
                ]
            ]
        },
        "container-title": "Oman Journal of Ophthalmology",
        "volume": "12",
        "issue": "3",
        "page": "171-176",
        "DOI": "10.4103/ojo.ojo_129_2018",
        "publisher": "Medknow Publications",
        "ISSN": "0974-620X",
        "abstract": "Purpose: This study aimed to report the comparison of recurrence rate and complications of intrapterygial injection of mitomycin C (MMC) 1 month before bare sclera excision of pterygium with and without conjunctival flap from the inferior bulbar conjunctiva.\n\nMethods: This prospective interventional study enrolled 60 patients of pterygia from November 2010 to June 2012. All eyes received 0.1 ml (0.02%) of intrapterygial MMC injection 1 month preoperatively. Patients were divided into two groups of 30 each: Group 1 - bare scleral excision (BSE) and Group 2 - BSE with conjunctival flap from the inferior bulbar conjunctiva to cover the bare sclera. Chi-square test, Fisher's exact test, and unpaired t-test were used for statistical analysis.\n\nResults: The mean age was 40.6 ± 12.8 years and 36.9 ± 10.9 years in Group 1 and 2, respectively, (P = 0.2329). There were 11 (36.7%) males and 19 (63.3%) females in Group 1 and 7 (23.3%) males and 23 (76.7%) females in Group 2 (P = 0.101). The recurrence rate was 0% in Group 1 and 3.3% (1 eye) in Group 2 (P = 1.00). Postoperatively, scleral whitening occurred in 6 (20%) eyes in Group 1 and none in Group 2 (P = 0.015).\n\nConclusion: Both techniques, BSE alone or with conjunctival flap from the inferior bulbar conjunctiva 1 month after intrapterygial MMC, resulted in negligible (0%-3.3%) recurrence of pterygium. Conjunctival flap significantly reduced (0%) the postoperative complication of scleral whitening. This is the first report of efficacy of conjunctival flap in reducing scleral whitening after intrapterygial MMC."
    }
]