[
    {
        "id": "osp-2202",
        "type": "article-journal",
        "title": "Mortality and Morbidity in HF rEF, HF mrEF, and HF pEF Patients with Diabetes in the Middle East",
        "author": [
            {
                "family": "Al Jarallah",
                "given": "Mohammed"
            },
            {
                "family": "Rajan",
                "given": "Rajesh"
            },
            {
                "family": "Al-Zakwani",
                "given": "Ibrahim"
            },
            {
                "family": "Dashti",
                "given": "Raja"
            },
            {
                "family": "Bulbanat",
                "given": "Bassam"
            },
            {
                "family": "Ridha",
                "given": "Mustafa"
            },
            {
                "family": "Sulaiman",
                "given": "Kadhim"
            },
            {
                "family": "Alsheikh-Ali",
                "given": "Alawi A."
            },
            {
                "family": "Panduranga",
                "given": "Prashanth"
            },
            {
                "family": "AlHabib",
                "given": "Khalid F."
            },
            {
                "family": "Al Suwaidi",
                "given": "Jassim"
            },
            {
                "family": "Al-Mahmeed",
                "given": "Wael"
            },
            {
                "family": "AlFaleh",
                "given": "Hussam"
            },
            {
                "family": "Elasfar",
                "given": "Abdelfatah"
            },
            {
                "family": "Al-Motarreb",
                "given": "Ahmed"
            },
            {
                "family": "Bazargani",
                "given": "Nooshin"
            },
            {
                "family": "Asaad",
                "given": "Nidal"
            },
            {
                "family": "Amin",
                "given": "Haitham"
            }
        ],
        "URL": "https://omanscience.com/en/articles/mortality-and-morbidity-in-hf-ref-hf-mref-and-hf-pef-patients-with-diabetes-in-the-middle-east",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2020
                ]
            ]
        },
        "container-title": "Oman Medical Journal",
        "DOI": "10.5001/omj.2020.17",
        "publisher": "Oman Medical Specialty Board",
        "ISSN": "1999-768X",
        "abstract": "Objectives: We sought to estimate the mortality and morbidity in diabetic acute heart failure (AHF) patients stratified by left ventricular ejection fraction. Methods: We analyzed the data of patients with AHF from seven Middle Eastern countries (Bahrain, Oman, Yemen, Kuwait, UAE, Qatar, and Saudi Arabia) from February to November 2012, who were enrolled in a multinational registry of patients with heart failure (HF). Results: A total of 2258 AHF patients had diabetes mellitus. The mean age was 63.0±11.0 years (ranging from 18 to 99 years), and 60.3% (n = 1362) of the patients were males. The mean ejection fraction (EF) was 37.0±13.0%. HF with reduced EF (< 40%) (HF rEF) was observed in 1268 patients (56.2%), whereas 515 patients (22.8%) had mid-range (40–49%) (HF mrEF) and 475 patients (21.0%) had preserved EF (≥ 50%) (HF pEF). The overall cumulative all-cause mortalities at three- and 12-months follow-up were 11.8% (n = 266) and 20.7% (n = 467), respectively. Those with HF pEF were associated with lower three-months cumulative all-cause mortality compared to those with HF rEF (7.6% vs. 5.9%; adjusted odds ratio (aOR) = 0.54, 95% confidence interval (CI): 0.31–0.95; p = 0.031), but not significantly different when compared to those with HF mrEF (aOR = 0.86, 95% CI: 0.53–1.40; p = 0.554). There were largely no significant differences among the groups with regards to the 12-months all-cause cumulative mortality (11% vs. 11% vs. 10%; p = 0.984). There were also no significant differences in re-hospitalization rates between the three HF groups not only at three months (23% vs. 20% vs. 22%; p = 0.520), but at one-year follow-up (28% vs. 30% vs. 32%; p = 0.335). Conclusions: Three-month cumulative all-cause mortality was high in diabetic HF rEF patients when compared to those with HF pEF. However, there were no significant differences in mortality at one-year follow-up between the HF groups. There were also no significant differences in re-hospitalization rates between the HF groups not only at three months but also at one-year follow-up in the Middle East."
    }
]