[
    {
        "id": "osp-12447",
        "type": "article-journal",
        "title": "Long term effect of panretinal photocoagulation on retinal nerve fiber layer parameters in patients with proliferative diabetic retinopathy",
        "author": [
            {
                "family": "Wadhwani",
                "given": "Meenakshi"
            },
            {
                "family": "Bali",
                "given": "Shweta"
            },
            {
                "family": "Bhartiya",
                "given": "Shibal"
            },
            {
                "family": "Mahabir",
                "given": "Manish"
            },
            {
                "family": "Upadhaya",
                "given": "Ashish"
            },
            {
                "family": "Dada",
                "given": "Tanuj"
            },
            {
                "family": "Sharma",
                "given": "Anu"
            },
            {
                "family": "Mishra",
                "given": "Sanjay Kumar"
            }
        ],
        "URL": "https://omanscience.com/en/articles/long-term-effect-of-panretinal-photocoagulation-on-retinal-nerve-fiber-layer-parameters-in-patients-with-proliferative-diabetic-retinopathy",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2019
                ]
            ]
        },
        "container-title": "Oman Journal of Ophthalmology",
        "volume": "12",
        "issue": "3",
        "page": "181-185",
        "DOI": "10.4103/ojo.ojo_39_2018",
        "publisher": "Medknow Publications",
        "ISSN": "0974-620X",
        "abstract": "Purpose: This study aimed to evaluate the long-term effect of panretinal photocoagulation (PRP) on the retinal nerve fiber layer (RNFL) in patients with proliferative diabetic retinopathy (PDR).\n\nMethods: This was a prospective longitudinal cohort study examining 42 eyes of 42 patients with PDR undergoing PRP. Peripapillary RNFL thickness (RNFLT) was measured using spectral-domain optical coherence tomography at baseline, 1 year, and 3 years following PRP.\n\nResults: The mean \"average RNFLT\" was 89.88 ± 14.26 μm at baseline, 85.75 ± 11.36 μm at 1-year follow-up, and 83.33 ± 11.96 μm at 3-year follow-up. There was a statistically significant difference in the average RNFL thickness at baseline and 1 year and 3 years after PRP. At 1-year follow-up, superior, inferior, and nasal RNFL measurements reduced significantly from baseline (P < 0.01). The reduction in RNFL remained statistically significant for superior and inferior quadrants 3 years after PRP.\n\nConclusion: PRP causes a reduction in RNFL thickness until 3 years after the procedure. Caution should be exercised while interpreting peripapillary RNFL thickness scans in patients who have undergone PRP for diabetic retinopathy."
    }
]