[
    {
        "id": "osp-2763",
        "type": "article-journal",
        "title": "Interference with Immunoassays of a Neonate on High Biotin: Case Report and Literature Review",
        "author": [
            {
                "family": "Al Shibli",
                "given": "Naeema"
            },
            {
                "family": "Al Shidhani",
                "given": "Azza"
            },
            {
                "family": "Ullah",
                "given": "Irfan"
            },
            {
                "family": "AlSaffar",
                "given": "Hussain"
            },
            {
                "family": "Al Kalbani",
                "given": "Faris"
            },
            {
                "family": "Al Farsi",
                "given": "Koukab"
            },
            {
                "family": "AlShekaili",
                "given": "Jalila"
            },
            {
                "family": "Al-Riyami",
                "given": "Nafila"
            }
        ],
        "URL": "https://omanscience.com/en/articles/interference-with-immunoassays-of-a-neonate-on-high-biotin-case-report-and-literature-review",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2024
                ]
            ]
        },
        "container-title": "Oman Medical Journal",
        "DOI": "10.5001/omj.2024.30",
        "publisher": "Oman Medical Specialty Board",
        "ISSN": "1999-768X",
        "abstract": "Biotin is sometimes administered in mega doses to children to treat certain inborn errors of metabolism. We report the case of a one-week-old newborn who was started on a ‘mitochondrial cocktail’ that contained a high dose of biotin. On day seven of life, his thyroid function test showed a biochemical picture of primary hyperthyroidism, which was not clinically evident. The suspicion of immunoassay interference with thyroid function test was confirmed when another lab, using a different immunoassay, gave normal results. If the biochemical profile does not match the clinical picture, it is reasonable to doubt the test result and think of assay interference."
    }
]