[
    {
        "id": "osp-12283",
        "type": "article-journal",
        "title": "Impact of COVID-19-related lockdown on retinal disorders treated with intravitreal injections",
        "author": [
            {
                "family": "Brar",
                "given": "Manpreet"
            },
            {
                "family": "Grewal",
                "given": "Satinder Pal Singh"
            },
            {
                "family": "Grewal",
                "given": "Dilraj S"
            },
            {
                "family": "Sharma",
                "given": "Mansi"
            },
            {
                "family": "Dogra",
                "given": "Mangat Ram"
            }
        ],
        "URL": "https://omanscience.com/en/articles/impact-of-covid-19-related-lockdown-on-retinal-disorders-treated-with-intravitreal-injections",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2022
                ]
            ]
        },
        "container-title": "Oman Journal of Ophthalmology",
        "volume": "15",
        "issue": "2",
        "page": "168-174",
        "DOI": "10.4103/ojo.ojo_74_21",
        "publisher": "Medknow Publications",
        "ISSN": "0974-620X",
        "abstract": "Purpose: To study functional changes in vision and morphological changes on optical coherence tomography (OCT) scans in patients where intravitreal therapy (IVT) with injections has been delayed due to COVID-19 pandemic lockdown.\n\nMethods: Retrospective cross-sectional study included 77 eyes with the diagnosis of exudative age-related macular degeneration (eAMD), diabetic macular edema (DME), and retinal vein occlusion (RVO), regularly receiving IVT with anti-vascular endothelial growth factor (Anti-VEGF) injections or dexamethasone implant and were not able to receive the injections as intended due to lockdown. Best-corrected visual acuity (BCVA), central foveal thickness (CFT), and qualitative morphological features on OCT were analyzed pre- and post-therapy break off.\n\nResults: The mean duration of IVT break-off was 57 days. Mean BCVA logarithm of minimum angle of resolution (logMAR) worsened from 0.33 (20/42) to 0.35 (40/44) (P = 0.02) and mean CFT increased from 297.90 μm to 402.16 μm (P < 0.01), from pretherapy break-off to return visit. Worsening of the visual acuity was seen across all the three disease cohorts, significantly more in the eyes with eAMD.\n\nConclusion: Marginal decline in the visual acuity and worsening of the OCT features were observed as a result of delay in the IVT injections of DME, eAMD and RVO patients."
    }
]