[
    {
        "id": "osp-11375",
        "type": "article-journal",
        "title": "Hepatitis B Vaccine Coverage and the Immune Response in Children under ten years old in Sana’a, Yemen",
        "author": [
            {
                "family": "Al-Shamahy",
                "given": "Hassan A."
            },
            {
                "family": "Hanash",
                "given": "Samira H."
            },
            {
                "family": "Al-Madhaji",
                "given": "Iqbal A."
            },
            {
                "family": "M.",
                "given": "Nameem"
            },
            {
                "family": "Naser",
                "given": "Samarih M."
            }
        ],
        "URL": "https://omanscience.com/en/articles/hepatitis-b-vaccine-coverage-and-the-immune-response-in-children-under-ten-years-old-in-sana-a-yemen",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2025
                ]
            ]
        },
        "container-title": "Sultan Qaboos University Medical Journal",
        "volume": "11",
        "issue": "1",
        "page": "77-82",
        "DOI": "10.18295/2075-0528.1242",
        "publisher": "Sultan Qaboos University",
        "ISSN": "2075-051X",
        "abstract": "Objectives: The study was undertaken, first, to determine the coverage rate of hepatitis B (HB) vaccine and second to evaluate the immune response to HB vaccine among children under 10 years old by measuring the level of circulating anti-HB surface antigen (anti-HBs) antibodies after immunisation with three doses. Methods: First, 840 children were randomly selected from 4 randomly selected sites in Sana'a city to study the coverage rate of the vaccine; of these, 504 children vaccinated against HBV prior to the study, were tested (56% males and 44% females). Sera were tested for anti-HBs antibodies by ELISA quantitative technique. Each individual’s data was collected in a pre-designed questionnaire including: vaccination date, sex, and age at the time of the study. Results: The coverage rate of HBV vaccine was only 69.9%, being slightly higher among male children (72.1%) than female children (66.8%). A total of 276 (54.8%) of the 504 children responded to the vaccine with anti-HBs antibody level ≥ 10 mIU/ml, while 228 (45.2%) of the 504 children had non-protective anti-HBs antibodies levels ("
    }
]