[
    {
        "id": "osp-10045",
        "type": "article-journal",
        "title": "Healthcare-Associated Infections Secondary to Multidrug-Resistant Organisms in Hospitalised Patients with COVID-19 Pneumonia: A single-centre experience",
        "author": [
            {
                "family": "Al Hanashi",
                "given": "Yahyia"
            },
            {
                "family": "Balkhair",
                "given": "Abdullah"
            }
        ],
        "URL": "https://omanscience.com/en/articles/healthcare-associated-infections-secondary-to-multidrug-resistant-organisms-in-hospitalised-patients-with-covid-19-pneumonia-a-single-centre-experienc",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2025
                ]
            ]
        },
        "container-title": "Sultan Qaboos University Medical Journal",
        "volume": "25",
        "issue": "1",
        "page": "186-190",
        "DOI": "10.18295/2075-0528.2826",
        "publisher": "Sultan Qaboos University",
        "ISSN": "2075-051X",
        "abstract": "Objectives: Hospitalisations related to COVID-19 pneumonia have increased the risk of healthcare-associated infections (HCAIs), including those caused by multidrug-resistant organisms (MDROs). This study aimed to investigate the epidemiology of HCAIs secondary to MDROs among hospitalised patients with COVID-19 pneumonia. Methods: This retrospective study population included patients with COVID-19 pneumonia aged 18 years and older who were admitted to Sultan Qaboos University Hospital, Muscat, Oman, for more than 48 hours between March 2020 and December 2021. Results: A total of 486 patients were included in this study. Among the cohort, 76 patients (15.6%) were diagnosed with concurrent HCAIs with an MDRO as the causative pathogen. Of these patients, 31 (40.8%) had infections caused by MDR Acinetobacter baumannii, 15 (19.7%) had infections secondary to carbapenem-resistant Klebsiella pneumoniae and 8 (10.5%) had infections caused by extended-spectrum betalactamase Escherichia coli. Pneumonia and bacteraemia were the two most common concurrent healthcare-associated MDRO infection sites, accounting for 42% and 36% of all events, respectively. Among the 486 patients, 155 died (31.9%). Among these, 64 (41.3%) had concurrent HCAIs caused by 1 or more MDROs. Contrarily, among the 331 patients with COVID-19 pneumonia who recovered, only 12 (3.6%) had concurrent HCAIs. Conclusions: There is high prevalence of healthcare-associated MDRO infections.predominantly pneumonia and bacteraemia.in hospitalised patients with COVID-19 pneumonia. This reveals a significant association between infection with MDROs and death underlining the substantial impact of infection with MDROs in this vulnerable patient population."
    }
]