[
    {
        "id": "osp-1306",
        "type": "article-journal",
        "title": "Effect of Thrombolytic Therapy on the Incidence of Early Left Ventricular Infarct Expansion in Acute Anterior Myocardial Infarction",
        "author": [
            {
                "family": "Al-Othman",
                "given": "Abdulkareem A."
            },
            {
                "family": "Al-Tawil",
                "given": "Namir Ghanim"
            }
        ],
        "URL": "https://omanscience.com/en/articles/effect-of-thrombolytic-therapy-on-the-incidence-of-early-left-ventricular-infarct-expansion-in-acute-anterior-myocardial-infarction",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2011
                ]
            ]
        },
        "container-title": "Oman Medical Journal",
        "DOI": "10.5001/omj.2011.109",
        "publisher": "Oman Medical Specialty Board",
        "ISSN": "1999-768X",
        "abstract": "Objectives: To determine the incidence of early left ventricular infarct expansion within five days after first anterior ST-segment elevation myocardial infarction and the effect of early thrombolytic therapy on the incidence of early infarct expansion compared with late thrombolytic therapy. Methods: In a prospective study of 101 patients (75 males and 26 females), with the first attack of acute anterior myocardial infarction, their ages ranged from 40-80 years (mean age: 61.07±10.78) who had been admitted to the Coronary Care Unit of Hawler Teaching Hospital for the period from July 2007 through to September 2009. Those who received alteplase ≤3 hours of acute myocardial infarction were labelled as group-I (49 patients) and those who received alteplase >3-12 hours were labelled as group-II (52 patients). Results: The incidence of early left ventricular infarct expansion was diagnosed by 2D-echocardiography and was found to be 17.8%. Group I patients had a lower incidence of early left ventricular infarct expansion (8.16%) compared with group-II (26.92%; p=0.014). Patients with early left ventricular infarct expansion had a higher frequency rate of left ventricular systolic dysfunction (94.44%) compared to patients without early left ventricular infarct expansion (8.43%; p"
    }
]