[
    {
        "id": "osp-12135",
        "type": "article-journal",
        "title": "Diverse presentations of ectopia lentis and lens coloboma in Marfan's syndrome",
        "author": [
            {
                "family": "Dhiman",
                "given": "Richa"
            },
            {
                "family": "Kaur",
                "given": "Lovepreet"
            },
            {
                "family": "Sharma",
                "given": "Nancy"
            },
            {
                "family": "Pandey",
                "given": "Mohan Lal"
            }
        ],
        "URL": "https://omanscience.com/en/articles/diverse-presentations-of-ectopia-lentis-and-lens-coloboma-in-marfan-s-syndrome",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2023
                ]
            ]
        },
        "container-title": "Oman Journal of Ophthalmology",
        "volume": "16",
        "issue": "2",
        "page": "310-313",
        "DOI": "10.4103/ojo.ojo_108_22",
        "publisher": "Medknow Publications",
        "ISSN": "0974-620X",
        "abstract": "Marfan's syndrome (MFS) is an autosomal dominant connective tissue disorder with defect in the fibrillin-1 gene. The most common ocular manifestation is subluxated lens in the superotemporal direction, accounting for 50%-85% of total cases. The association of lens coloboma with MFS has been described in literature, but the coexistence of lens coloboma with ectopia lentis is a rare feature. Here, we describe three cases of MFS including a case of bilateral lens coloboma with ectopia lentis: case 1 - a 39-year-old male with inferotemporal lens subluxation in the right eye and superotemporal lens subluxation in the left eye with open-angle glaucoma and high myopia, case 2 - a 15-year-old child with bilateral superonasal lens subluxation with lens coloboma, and case 3 - a 56-year-old female with bilateral lens coloboma. Case 1 and case 2 had clear lenses with good refractive correction; hence, they were optically rehabilitated with contact lenses, whereas case 3 was advised for cataract surgery. It is important to distinguish the lens coloboma from a more common entity, ectopia lentis as former usually remains stable while the latter might need a surgical intervention."
    }
]