[
    {
        "id": "osp-10129",
        "type": "article-journal",
        "title": "Bloodstream Infection in Children Managed at a Tertiary Hospital in Oman",
        "author": [
            {
                "family": "Al Saeghi",
                "given": "Nadiya"
            },
            {
                "family": "Al Thuhli",
                "given": "Marwah"
            },
            {
                "family": "Al Hamrashi",
                "given": "Hajer"
            },
            {
                "family": "Al Shibli",
                "given": "Naema"
            },
            {
                "family": "Al-Wahaibi",
                "given": "Adil"
            },
            {
                "family": "Al-Adawi",
                "given": "Badriya"
            },
            {
                "family": "Al Yazidi",
                "given": "Laila"
            }
        ],
        "URL": "https://omanscience.com/en/articles/bloodstream-infection-in-children-managed-at-a-tertiary-hospital-in-oman",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2025
                ]
            ]
        },
        "container-title": "Sultan Qaboos University Medical Journal",
        "volume": "24",
        "issue": "4",
        "page": "501-506",
        "DOI": "10.18295/squmj.7.2024.044",
        "publisher": "Sultan Qaboos University",
        "ISSN": "2075-051X",
        "abstract": "Objectives: This study aimed to assess the local epidemiology and outcome of bloodstream infection (BSI) among Omani children. Methods: This retrospective study was conducted at Sultan Qaboos University Hospital, Muscat, Oman, over 5 years (2014–2018) and included laboratory-confirmed BSI among children aged 0–12 years old. Patients’ demographic, clinical and laboratory data were extracted from the hospital’s electronic records and used to assess BSI rates and outcomes. Results: A total of 1,253 positive blood cultures were identified, of which 592 (47.2%) were regarded as contaminants. Overall, 404 (32.2%) significant episodes of BSI were identified in 272 patients; 346 (85.6%) significant episodes were in children aged ≤5 years and 366 (90.6%) had comorbidities. The 5-year incidence of BSI was 13 per 1,000 admissions. Furthermore, 333 (82.4%) episodes were healthcare-related infections. Enterobacterales (n = 152; 37.6%) were the most common organisms identified followed by coagulase-negative staphylococci (n = 63; 15.6%). Approximately 40% of Gram-negative organisms were resistant to third-generation cephalosporins. The crude mortality rate at 30 days was 9.2%. Paediatric intensive care unit admission (crude odds ratio [COR] = 2.24, 95% confidence interval [CI]: 0.98–4.78) and the presence of graft-versus-host disease (COR = 7.99, 95% CI: 1.52–37.76) were associated with increased death within 30 days. The multivariate logistic regression analysis showed that Pseudomonas aeruginosa (adjusted odds ratio = 18.46, 95% CI: 3.96–97.84) was the only independent predictor of increasing 30-day mortality in this cohort. Conclusion: A high rate of hospital-related BSI was found in children in Oman, highlighting the need to optimise infection control strategies and the care of central vein access devices."
    }
]