[
    {
        "id": "osp-10047",
        "type": "article-journal",
        "title": "Anti-Neutrophil Cytoplasmic Antibody-Associated Central and Peripheral Nervous System Vasculitis",
        "author": [
            {
                "family": "Oommen",
                "given": "Abel T."
            },
            {
                "family": "Gujjar",
                "given": "Arunodaya R."
            },
            {
                "family": "Al Jahdhami",
                "given": "Suad"
            },
            {
                "family": "Al-Asmi",
                "given": "Abdullah R."
            },
            {
                "family": "Sajjad",
                "given": "Ali"
            }
        ],
        "URL": "https://omanscience.com/en/articles/anti-neutrophil-cytoplasmic-antibody-associated-central-and-peripheral-nervous-system-vasculitis",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2025
                ]
            ]
        },
        "container-title": "Sultan Qaboos University Medical Journal",
        "volume": "25",
        "issue": "1",
        "page": "282-287",
        "DOI": "10.18295/2075-0528.2820",
        "publisher": "Sultan Qaboos University",
        "ISSN": "2075-051X",
        "abstract": "The anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) usually manifests as systemic vasculitis. AAV with central nervous system involvement in the form of mesenrhombencephalitis and peripheral neuropathy is extremely rare. We report a 59-year-old male patient who presented to a tertiary care hospital in Muscat, Oman, in 2024. He had a subacute presentation of altered sensorium, multiple cranial nerve palsy and ataxia with 3 months history of bilateral foot drop. Brain imaging was suggestive of mesenrhombencephalitis with subarachnoid and intraparenchymal haemorrhage. Nerve conduction studies revealed sensorimotor axonal neuropathy. Vasculitis profile showed perinuclear-ANCA positivity and the nerve biopsy was suggestive of vasculitic neuropathy. He was treated with intravenous steroids and maintained on rituximab. His neurological deficits improved with residual bilateral foot drop."
    }
]