[
    {
        "id": "osp-13635",
        "type": "article-journal",
        "title": "A Terbium Sensitized Luminescence Method for the Assay of Flubiprofen in Pharmaceutical Formulations",
        "author": [
            {
                "family": "Al‐Kindy",
                "given": "Salma M.Z."
            },
            {
                "family": "Al-Ghazali",
                "given": "Arwa"
            },
            {
                "family": "Suliman",
                "given": "Fakhr Eldin O."
            },
            {
                "family": "Al-Lawati",
                "given": "Haidar A.J."
            }
        ],
        "URL": "https://omanscience.com/en/articles/a-terbium-sensitized-luminescence-method-for-the-assay-of-flubiprofen-in-pharmaceutical-formulations",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2014
                ]
            ]
        },
        "container-title": "Sultan Qaboos University Journal for Science",
        "volume": "19",
        "issue": "1",
        "page": "54",
        "DOI": "10.24200/squjs.vol19iss1pp54-63",
        "publisher": "Sultan Qaboos University",
        "ISSN": "2308-3921",
        "abstract": "A sensitive time-resolved luminescence method for the determination of flubiprofen (FLP) in methanol and in aqueous solution is described. The method is based on the luminescence sensitization of terbium (Tb3+ ) by the formation of a ternary complex with FLP in the presence of 4,7 diphenyl 1,10 phenanthroline (DPP) as co-ligand, and Tween-20 as surfactant. The signal for Tb-FLP-DPP was monitored at λex = 285 nm and λem = 552 nm. Optimum conditions for the formation of the complex in an aqueous system were TRIS buffer, pH 8.0, DPP (2.5Å~10−7 M), Tween-20 (0.30%) and 4Å~10-5 mol L-1 of Tb3+ which allowed the determination of 20–1000 ng mL-1 of FLP with a limit of detection (LOD) of 10 ng mL-1 . The relative standard deviations of the method ranged between 0.6 and 1.4% indicating excellent reproducibility of the method. The proposed method was successfully applied for the assays of FLP in pharmaceutical formulations and spiked tap water samples with average recoveries of 87% – 95%."
    }
]