[
    {
        "id": "osp-11378",
        "type": "article-journal",
        "title": "VIPoma Crisis: Immediate and life saving reduction of massive stool volumes on starting treatment with octreotide",
        "author": [
            {
                "family": "Elshafie",
                "given": "Omayma"
            },
            {
                "family": "Grant",
                "given": "Christopher"
            },
            {
                "family": "Jain",
                "given": "Aisha"
            },
            {
                "family": "Rajeev",
                "given": ""
            },
            {
                "family": "Woodhouse",
                "given": "Nicholas"
            }
        ],
        "URL": "https://omanscience.com/ar/articles/vipoma-crisis-immediate-and-life-saving-reduction-of-massive-stool-volumes-on-starting-treatment-with-octreotide",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2025
                ]
            ]
        },
        "container-title": "Sultan Qaboos University Medical Journal",
        "volume": "11",
        "issue": "1",
        "page": "104-107",
        "DOI": "10.18295/2075-0528.1245",
        "publisher": "Sultan Qaboos University",
        "ISSN": "2075-051X",
        "abstract": "We report the case of a 57-year-old male physician who presented with a life threatening secretory and refractory diarrhoea of around 20 L/day. This was complicated by severe hypotension, hypokalaemia, hypercalcaemia, renal failure requiring dialysis, metabolic acidosis, cardiorespiratory arrest and ventilation for 12 days. His diarrhoea responded immediately to the first dose of a therapeutic trial of subcutaneous octreotide 100 mcg 8 hourly which was started on clinical grounds alone before any investigations were carried out. After one day he was extubated and his blood pressure returned to normal. When a functioning neuroendocrine tumour is suspected clinically, the use of octreotide can, as in this case, be life saving."
    }
]