[
    {
        "id": "osp-9948",
        "type": "article-journal",
        "title": "The Correlation Between Zinc Intake and Superoxide Dismutase Activity with Cognitive Function in the Elderly",
        "author": [
            {
                "family": "Khuzaimah",
                "given": "Rima"
            },
            {
                "family": "Witjaksono",
                "given": "Fiastuti"
            },
            {
                "family": "Hardiany",
                "given": "Novi Silvia"
            }
        ],
        "URL": "https://omanscience.com/ar/articles/the-correlation-between-zinc-intake-and-superoxide-dismutase-activity-with-cognitive-function-in-the-elderly",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2025
                ]
            ]
        },
        "container-title": "Sultan Qaboos University Medical Journal",
        "volume": "25",
        "issue": "1",
        "page": "506-514",
        "DOI": "10.18295/2075-0528.2866",
        "publisher": "Sultan Qaboos University",
        "ISSN": "2075-051X",
        "abstract": "Objectives: This study aimed to analyse the correlation between zinc intake and superoxide dismutase (SOD) with cognitive function in the elderly. Thus, the role of zinc as a structural component of SOD, along with SOD’s contribution to cognitive function, can be established. Methods: This cross-sectional study was conducted at Panti Sosial Tresna Wredha Budi Mulia 1 in Jakarta, Indonesia, from July to September 2024. Elderly men and women were included. Zinc intake was assessed using the Semi-Quantitative Food Frequency Questionnaire, while plasma SOD activity was measured by spectrophotometer. Cognitive function was assessed using the Montreal Cognitive Assessment-Indonesia version. Data were analysed using bivariate testing and multivariate linear regression. Results: A total of 85 subjects were included with a median age of 69 years (61.2% were female and 38.8% male). The majority (72.9%) had primary-level education and 87.1% had chronic diseases. The mean physical activity score was 75.4 ± 39.8, the mean body mass index was 21.8 ± 3.9 kg/m2 and the median daily calorie intake was 1,927.8 kcal/day (range: 1,341.7–2,167.0 kcal/day). No correlation was found between zinc intake and cognitive function. However, a significant correlation (P = 0.006, r = 0.296) was observed between SOD levels and cognitive function, with multivariate analysis indicating that gender, education and SOD accounted for 15.9% of the variance in cognitive function. Conclusion: This study found no significant correlation between zinc intake and cognitive function. However, SOD activity were significantly correlated with cognitive function in the elderly."
    }
]