[
    {
        "id": "osp-10072",
        "type": "article-journal",
        "title": "Successful Treatment of a Case of Crescentic Glomerulonephritis in a Patient with Primary Peritoneal Carcinoma: A case report",
        "author": [
            {
                "family": "Zribi",
                "given": "Aref"
            },
            {
                "family": "Nagy",
                "given": "Amro"
            },
            {
                "family": "Al Riyami",
                "given": "Marwa"
            },
            {
                "family": "Burney",
                "given": "Ikram A."
            }
        ],
        "URL": "https://omanscience.com/ar/articles/successful-treatment-of-a-case-of-crescentic-glomerulonephritis-in-a-patient-with-primary-peritoneal-carcinoma-a-case-report",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2025
                ]
            ]
        },
        "container-title": "Sultan Qaboos University Medical Journal",
        "volume": "24",
        "issue": "1",
        "page": "119-122",
        "DOI": "10.18295/squmj.1.2023.013",
        "publisher": "Sultan Qaboos University",
        "ISSN": "2075-051X",
        "abstract": "Crescentic glomerulonephritis has been associated with several solid tumour malignancies. Only a few cases of nephropathy have been reported in association with tubo-ovarian/peritoneal malignancies. We report a 55-year-old female patient who presented to a tertiary care centre, Muscat, Oman, in 2022. She developed combined immune complex-mediated glomerulonephritis and pauci-immune necrotising crescentic vasculitis simultaneously with the diagnosis of tubo-ovarian/peritoneal cancer. The baseline estimated glomerular filtration rate (eGFR) was 13 mL/min. The patient received two doses of rituximab and three doses of pulse corticosteroids, leading to significant improvement in renal function and the disappearance of her proteinuria. The eGFR improved to >60mL/min; her proteinuria gradually resolved after 10 weeks of treatment. She was then given a combination chemotherapy treatment for tubo-ovarian/peritoneal cancer leading to a normalisation of her CA-125 after three months of therapy.\n\nKeywords: Peritoneal Neoplasm; Glomerulonephritis; Vasculitis; Chemotherapy; Case Report; Oman."
    }
]