[
    {
        "id": "osp-12676",
        "type": "article-journal",
        "title": "Radiotherapy for iris metastasis from esophageal carcinoma: A series of three cases",
        "author": [
            {
                "family": "Das",
                "given": "Chandana"
            },
            {
                "family": "Shields",
                "given": "Carol L"
            }
        ],
        "URL": "https://omanscience.com/ar/articles/radiotherapy-for-iris-metastasis-from-esophageal-carcinoma-a-series-of-three-cases",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2016
                ]
            ]
        },
        "container-title": "Oman Journal of Ophthalmology",
        "volume": "9",
        "issue": "2",
        "page": "93-96",
        "DOI": "10.4103/0974-620x.184526",
        "publisher": "Medknow Publications",
        "ISSN": "0974-620X",
        "abstract": "Background: Description of three cases of metastatic esophageal carcinoma to the iris and focus on management strategies.\n\nMethods: A 48-year-old man (Case 1) with previously treated stage IV esophageal carcinoma presented with blurred vision in the left eye (OS) for 3 weeks. Initial fine needle aspiration biopsy (FNAB) was negative for malignant cells, so incisional biopsy was performed and confirmed metastatic carcinoma. A 53-year-old man (Case 2) with previously treated stage III esophageal cancer experienced 2 months of pain and 1 month of blurred vision OS. Documented tumor growth suggested esophageal carcinoma metastasis. A 65-year-old man (Case 3) with previously treated stage IV esophageal carcinoma developed hyphema in the right eye (OD), and FNAB confirmed metastatic carcinoma.\n\nResults: Case 1 was treated with external beam radiotherapy (EBRT), delivered over 16 days which resulted in complete tumor regression. Case 2 received stereotactic body radiotherapy (SBRT) over 21 days leading to complete tumor regression. Case 3 was treated with plaque radiotherapy over 4 days, resulting in complete tumor regression.\n\nConclusions: In all three cases, radiotherapy was employed, and enucleation was avoided. Plaque radiotherapy achieved tumor control in a shorter period of time (4 days) compared to EBRT (16 days) or SBRT (21 days). Knowing the short life expectancy of these patients, plaque radiotherapy appears most favorable."
    }
]