[
    {
        "id": "osp-11169",
        "type": "article-journal",
        "title": "Is Cerebrospinal Fluid C-reactive Protein a Better Tool than Blood C-reactive Protein in Laboratory Diagnosis of Meningitis in Children?",
        "author": [
            {
                "family": "Malla",
                "given": "Kalpana K."
            },
            {
                "family": "Malla",
                "given": "Tejesh"
            },
            {
                "family": "Basnet",
                "given": "K Seshagiri"
            },
            {
                "family": "Sahisnuta",
                "given": ""
            },
            {
                "family": "Shah",
                "given": "Ravi"
            }
        ],
        "URL": "https://omanscience.com/ar/articles/is-cerebrospinal-fluid-c-reactive-protein-a-better-tool-than-blood-c-reactive-protein-in-laboratory-diagnosis-of-meningitis-in-children",
        "language": "en",
        "issued": {
            "date-parts": [
                [
                    2025
                ]
            ]
        },
        "container-title": "Sultan Qaboos University Medical Journal",
        "volume": "13",
        "issue": "1",
        "page": "93-99",
        "DOI": "10.18295/2075-0528.1435",
        "publisher": "Sultan Qaboos University",
        "ISSN": "2075-051X",
        "abstract": "Objectives: This study aimed to test whether C-reactive protein (CRP) measurement could differentiate between different types of meningitis and become a routine test. Methods: A prospective study included 140 children admitted to Manipal Teaching Hospital, Pokhara, Nepal, between July 2009 and June 2011. The subjects had a blood test and detailed cerebrospinal fluid (CSF) analysis, including blood and CSF CRP levels. Results: Of those admitted, 31.1% had pyogenic meningitis (PM), 26.2% partially treated meningitis (PPM), 33% viral meningitis (VM), and 9.7% tubercular meningitis (TBM), with 26.4% controls. Organisms were isolated in 12.5% of the cases by blood culture and 25% of cases through CSF culture. Blood CRP was positive in all groups, with the highest values in PM (53.12 ± 28.88 mg/dl) and PPM (47.55 ± 34.34 mg/dl); this was not statistically significant (P = 0.08). The CSF CRP levels were significantly higher (P"
    }
]